Gene Symbol | Ffar4 |
Entrez Gene ID | 294075 |
Full Name | free fatty acid receptor 4 |
Synonyms | Gpr120,O3far1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ffar4 cDNA ORF clone
Gene Symbol | Ffar4 |
Entrez Gene ID | 294075 |
Full Name | free fatty acid receptor 4 |
Synonyms | Gpr120,O3far1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001047088.1 | NP_001040553.1 | free fatty acid receptor 4 |
Homo sapiens (human) | FFAR4 | NP_859529.2 |
Gallus gallus (chicken) | O3FAR1 | XP_003641529.2 |
Xenopus tropicalis (tropical clawed frog) | ffar4 | XP_002937240.2 |
Rattus norvegicus (Norway rat) | Ffar4 | NP_001040553.1 |
Pan troglodytes (chimpanzee) | O3FAR1 | XP_001148225.1 |
Mus musculus (house mouse) | Ffar4 | NP_861413.1 |
LOC700014 | XP_002808552.1 | |
Canis lupus familiaris (dog) | O3FAR1 | NP_001245268.1 |
Bos taurus (cattle) | LOC533266 | XP_002698434.1 |
GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy.
Satapati S, Qian Y, Wu MS, Petrov A, Dai G, Wang SP, Zhu Y, Shen X, Muise ES, Chen Y, Zycband E, Weinglass A, Di Salvo J, Debenham JS, Cox JM, Lan P, Shah V, Previs SF, Erion M, Kelley DE, Wang L, Howard AD, Shang J
Journal of lipid research58(8)1561-1578(2017 Aug)
Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states.
Zhang D, So WY, Wang Y, Wu SY, Cheng Q, Leung PS
Clinical science (London, England : 1979)131(3)247-260(2017 Feb)
Arachidonic acid triggers [Ca2+]i increases in rat round spermatids by a likely GPR activation, ERK signalling and ER/acidic compartments Ca2+ release.
Paillamanque J, Sanchez-Tusie A, Carmona EM, Trevi?o CL, Sandoval C, Nualart F, Osses N, Reyes JG
PloS one12(2)e0172128(2017)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
GPR120 expression in beta-cells and GPR120-mediated insulinotropic effects are altered in obesity and diabetic states in distinct ways, and these alterations may be mediated by PPARgamma.
Title: Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states.
Data show that G protein-coupled receptor 120 protein (GPR120) appears strongly on interstitial cells and also on spermatogenic cells.
Title: Arachidonic acid triggers [Ca2+]i increases in rat round spermatids by a likely GPR activation, ERK signalling and ER/acidic compartments Ca2+ release.
demonstrated a GPR120-mediated novel anti-inflammatory pathway in specific intestinal epithelial cell types that could be of therapeutic relevance to intestinal inflammatory disorders
Title: A novel anti-inflammatory role of GPR120 in intestinal epithelial cells.
results indicated that the beneficial metabolic role of DHA was attributed to its ability to regulate glucose via the GPR120-mediated AMPK pathway in the skeletal muscles
Title: Endogenous Ligand for GPR120, Docosahexaenoic Acid, Exerts Benign Metabolic Effects on the Skeletal Muscles via AMP-activated Protein Kinase Pathway.
opposite effects of GPR120 and GPR40 may be involved in the cell motile activity stimulated by ethionine in WB-F344 cells
Title: Opposite effects of GPR120 and GPR40 on cell motile activity induced by ethionine in liver epithelial cells.
The following Ffar4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ffar4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa09811 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047088.1 | |
Accession Version | NM_001047088.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | free fatty acid receptor 4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB207868.1. On or before Sep 7, 2006 this sequence version replaced XM_215281.4, XM_001080642.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB207868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCCCTG AGTGTGCGCA GACGACGGGC CCTGGCCCCT CGCGCACCCC GGACCAAGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040553.1 |
CDS | 46..1131 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047088.1 |
1 | ATGTCCCCTG AGTGTGCGCA GACGACGGGC CCTGGCCCCT CGCGCACCCC GGACCAAGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy. |
Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states. |
Arachidonic acid triggers [Ca2+]i increases in rat round spermatids by a likely GPR activation, ERK signalling and ER/acidic compartments Ca2+ release. |