| Gene Symbol | Dlg5 |
| Entrez Gene ID | 305645 |
| Full Name | discs large MAGUK scaffold protein 5 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Dlg5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dlg5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa20102 | |
| Clone ID Related Accession (Same CDS sequence) | XM_003751423.4 , XM_003752781.4 , NM_001372003.1 | |
| Accession Version | NM_001372003.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5778bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-30 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07016833.1, AABR07016834.1 and AW520410.1. On or before Jul 31, 2019 this sequence version replaced XM_003751423.4, XM_003752781.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## | |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001358932.1 |
| CDS | 236..6013 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001372003.1 |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa20102 | |
| Clone ID Related Accession (Same CDS sequence) | XM_003751423.4 , XM_003752781.4 , NM_001372003.1 | |
| Accession Version | XM_003751423.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5778bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003751423.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_003751471.1 |
| CDS | 42..5819 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_003751423.4 |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa20102 | |
| Clone ID Related Accession (Same CDS sequence) | XM_003751423.4 , XM_003752781.4 , NM_001372003.1 | |
| Accession Version | XM_003752781.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5778bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000083.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003752781.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_003752829.1 |
| CDS | 41..5818 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_003752781.4 |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa36486 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008767364.2 , XM_006251620.3 | |
| Accession Version | XM_008767364.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5634bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000083.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767364.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008765586.1 |
| CDS | 41..5674 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008767364.2 |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa36486 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008767364.2 , XM_006251620.3 | |
| Accession Version | XM_006251620.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5634bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251620.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006251682.1 |
| CDS | 42..5675 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006251620.3 |
1 | ATGGAGCCGC AGCGCCGGGA GCTGCTCGCC CAGTGTCAGC AGAGCTTGGC CCAGGCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa46325 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008767368.2 | |
| Accession Version | XM_008767368.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5448bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | disks large homolog 5 isoform X3 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000083.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767368.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCCTCAG ACTCGGAGAG CAGCAGCTCC CTCAGCAGTG TGGGGACTAC AGGGAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008765590.1 |
| CDS | 90..5537 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008767368.2 |
1 | ATGCCCTCAG ACTCGGAGAG CAGCAGCTCC CTCAGCAGTG TGGGGACTAC AGGGAAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway. |
DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. |
Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5. |
Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. |
Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. |
