Gene Symbol | Mtpap |
Entrez Gene ID | 307050 |
Full Name | mitochondrial poly(A) polymerase |
Synonyms | Papd1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Mtpap cDNA ORF clone
Gene Symbol | Mtpap |
Entrez Gene ID | 307050 |
Full Name | mitochondrial poly(A) polymerase |
Synonyms | Papd1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006254071.3 | XP_006254133.1 | poly(A) RNA polymerase, mitochondrial isoform X1 |
NM_001107359.1 | NP_001100829.1 | poly(A) RNA polymerase, mitochondrial |
Homo sapiens (human) | MTPAP | NP_060579.3 |
Canis lupus familiaris (dog) | MTPAP | XP_535150.2 |
Mus musculus (house mouse) | Mtpap | NP_080433.1 |
Rattus norvegicus (Norway rat) | Mtpap | NP_001100829.1 |
Danio rerio (zebrafish) | LOC563801 | XP_692256.4 |
Bos taurus (cattle) | MTPAP | XP_002692192.2 |
Drosophila melanogaster (fruit fly) | CG11418 | NP_001259129.1 |
Xenopus tropicalis (tropical clawed frog) | mtpap | XP_002940378.2 |
Pan troglodytes (chimpanzee) | MTPAP | XP_001136690.1 |
MTPAP | XP_001083177.1 | |
Gallus gallus (chicken) | MTPAP | XP_418580.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003293 | XP_319519.4 |
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)
Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase.
Bai Y, Srivastava SK, Chang JH, Manley JL, Tong L
Molecular cell41(3)311-20(2011 Feb)
Defective mitochondrial mRNA maturation is associated with spastic ataxia.
Crosby AH, Patel H, Chioza BA, Proukakis C, Gurtz K, Patton MA, Sharifi R, Harlalka G, Simpson MA, Dick K, Reed JA, Al-Memar A, Chrzanowska-Lightowlers ZM, Cross HE, Lightowlers RN
American journal of human genetics87(5)655-60(2010 Nov)
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.
Mullen TE, Marzluff WF
Genes & development22(1)50-65(2008 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our molecular investigation of an autosomal-recessive spastic ataxia with optic atrophy, present among the Old Order Amish, identified a mutation of MTPAP associated with the disease phenotype.
Title: Defective mitochondrial mRNA maturation is associated with spastic ataxia.
The following Mtpap gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mtpap cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa00083 | |
Clone ID Related Accession (Same CDS sequence) | NM_001107359.1 | |
Accession Version | NM_001107359.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) RNA polymerase, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474030.1. On or before Oct 4, 2007 this sequence version replaced XM_225468.4, XM_001056452.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGTTTTTAG ATTTAGACGA AACTGGAAAT CTCAGTGATC ACAAGAATAC AGGGAATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001100829.1 |
CDS | 746..1756 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001107359.1 |
1 | ATGTTTTTAG ATTTAGACGA AACTGGAAAT CTCAGTGATC ACAAGAATAC AGGGAATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa37963 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254071.3 | |
Accession Version | XM_006254071.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) RNA polymerase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254071.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTCGCAC AGAAGCCGGC TGACCTCTGG CGTTTACTTC CTGCTGCCGT GACAATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006254133.1 |
CDS | 27..1835 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006254071.3 |
1 | ATGCTCGCAC AGAAGCCGGC TGACCTCTGG CGTTTACTTC CTGCTGCCGT GACAATGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. |
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. |
Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. |
Defective mitochondrial mRNA maturation is associated with spastic ataxia. |
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'. |