Gene Symbol | Nectin2 |
Entrez Gene ID | 308417 |
Full Name | nectin cell adhesion molecule 2 |
Synonyms | Pvrl2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Nectin2 cDNA ORF clone
Gene Symbol | Nectin2 |
Entrez Gene ID | 308417 |
Full Name | nectin cell adhesion molecule 2 |
Synonyms | Pvrl2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006228421.2 | XP_006228483.1 | nectin-2 isoform X1 |
NM_001012064.1 | NP_001012064.1 | nectin-2 precursor |
Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).
Deuss FA, Gully BS, Rossjohn J, Berry R
The Journal of biological chemistry292(27)11413-11422(2017 07)
Identification of CD112R as a novel checkpoint for human T cells.
Zhu Y, Paniccia A, Schulick AC, Chen W, Koenig MR, Byers JT, Yao S, Bevers S, Edil BH
The Journal of experimental medicine213(2)167-76(2016 Feb)
Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers.
Oshima T, Sato S, Kato J, Ito Y, Watanabe T, Tsuji I, Hori A, Kurokawa T, Kokubo T
Molecular cancer1260(2013 Jun)
Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.
Sipe CW, Liu L, Lee J, Grimsley-Myers C, Lu X
Development (Cambridge, England)140(8)1785-95(2013 Apr)
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
Samanta D, Ramagopal UA, Rubinstein R, Vigdorovich V, Nathenson SG, Almo SC
Proceedings of the National Academy of Sciences of the United States of America109(37)14836-40(2012 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cells transfected with the dynamin 3 construct had less uniformly distributed nectin 2 at intercellular contacts when compared to control cells.
Title: The role of dynamin 3 in the testis.
The following Nectin2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nectin2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa02128 | |
Clone ID Related Accession (Same CDS sequence) | NM_001012064.1 | |
Accession Version | NM_001012064.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-02-04 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | nectin-2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC090075.1. On Feb 11, 2005 this sequence version replaced XM_218427.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090075.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCCCGGG CCGCAGTCCT CCCGCCGTCC AGATTGTCAC CGACGCTGCC GTTGTTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001012064.1 |
CDS | 213..1805 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001012064.1 |
1 | ATGGCCCGGG CCGCAGTCCT CCCGCCGTCC AGATTGTCAC CGACGCTGCC GTTGTTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa22409 | |
Clone ID Related Accession (Same CDS sequence) | XM_006228421.2 | |
Accession Version | XM_006228421.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | nectin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228421.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCCGGG CCGCAGTCCT CCCGCCGTCC AGATTGTCAC CGACGCTGCC GTTGTTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006228483.1 |
CDS | 245..1648 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006228421.2 |
1 | ATGGCCCGGG CCGCAGTCCT CCCGCCGTCC AGATTGTCAC CGACGCTGCC GTTGTTGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT). |
Identification of CD112R as a novel checkpoint for human T cells. |
Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers. |
Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization. |
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion. |