• English
  • Sign In
    Please Sign In
    Sign In
    New to GenScript?
    Register
  • Contact Us
×
Contact us now: +1-877-436-7274

Klk12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Klk12
Entrez Gene ID 308564
Full Name kallikrein related-peptidase 12
Synonyms Klnk
General protein information
Preferred Names

kallikrein related-peptidase 12

Names

kallikrein-12
kallikrein 12
kallikrein k
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

1

1q22

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001107508.1 NP_001100978.1 kallikrein-12
XM_008759351.1 XP_008757573.1 kallikrein-12 isoform X1

Pathways from BioSystems


Homologies


Homo sapiens (human) KLK12 NP_665901.1
Canis lupus familiaris (dog) KLK12 XP_854572.1
Pan troglodytes (chimpanzee) KLK12 XP_001174137.1
Bos taurus (cattle) KLK12 NP_001180119.1
Mus musculus (house mouse) Klk12 NP_081373.1
Rattus norvegicus (Norway rat) Klk12 NP_001100978.1

Gene Ontology


Bibliography

Related articles in PubMed

Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors.
Guillon-Munos A, Oikonomopoulou K, Michel N, Smith CR, Petit-Courty A, Canepa S, Reverdiau P, Heuz?-Vourc'h N, Diamandis EP, Courty Y
The Journal of biological chemistry286(29)25505-18(2011 Jul)

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Iwai N, Yasui N, Naraba H, Tago N, Yamawaki H, Sumiya H
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)

Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Shinmura K, Tao H, Yamada H, Kataoka H, Sanjar R, Wang J, Yoshimura K, Sugimura H
Human mutation24(3)273-4(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Klk12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klk12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa11277 NM_001107508.1
Latest version!		 Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
ORa22716 XM_008759351.1
Latest version!		 Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa11277
Clone ID Related Accession (Same CDS sequence) NM_001107508.1
Accession Version NM_001107508.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 543bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-05-27
Organism Rattus norvegicus(Norway rat)
Product kallikrein-12
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_218644.4, XM_001080413.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689600, SAMN02642690 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC 
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT 
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC 
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA 
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT 
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT 
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG 
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA 
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC 
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001100978.1
CDS164..706
Translation

Target ORF information:

RefSeq Version NM_001107508.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001107508.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC 
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT 
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC 
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA 
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT 
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT 
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG 
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA 
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC 
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa22716
Clone ID Related Accession (Same CDS sequence) XM_008759351.1
Accession Version XM_008759351.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product kallikrein-12 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG 
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC 
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT 
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT 
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC 
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC 
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT 
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC 
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA 
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA 
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT 
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC 
AGAGTAGTCA TCAGGAACAA CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008757573.1
CDS43..786
Translation

Target ORF information:

RefSeq Version XM_008759351.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008759351.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG 
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC 
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT 
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT 
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC 
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC 
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT 
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC 
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA 
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA 
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT 
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC 
AGAGTAGTCA TCAGGAACAA CTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors.
The Journal of biological chemistry286(29)25505-18(2011 Jul)
Guillon-Munos A,Oikonomopoulou K,Michel N,Smith CR,Petit-Courty A,Canepa S,Reverdiau P,Heuz?-Vourc'h N,Diamandis EP,Courty Y


book

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)
Iwai N,Yasui N,Naraba H,Tago N,Yamawaki H,Sumiya H


book

Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Human mutation24(3)273-4(2004 Sep)
Shinmura K,Tao H,Yamada H,Kataoka H,Sanjar R,Wang J,Yoshimura K,Sugimura H