Fbxl17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Fbxl17
Entrez Gene ID	316663
Full Name	F-box and leucine-rich repeat protein 17
General protein information	Preferred Names F-box and leucine-rich repeat protein 17 Names F-box/LRR-repeat protein 17
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q37

mRNA and Protein(s)

mRNA Protein Name

NM_001108235.1 NP_001101705.1 F-box/LRR-repeat protein 17
Pathways from BioSystems

mRNA	Protein	Name
NM_001108235.1	NP_001101705.1	F-box/LRR-repeat protein 17

Homologies

Canis lupus familiaris (dog)	FBXL17	XP_850192.3
Mus musculus (house mouse)	Fbxl17	NP_056609.1
Danio rerio (zebrafish)	LOC795023	XP_001335097.5
	LOC710818	XP_002808481.1
Rattus norvegicus (Norway rat)	Fbxl17	NP_001101705.1
Gallus gallus (chicken)	FBXL17	XP_004949350.1
Homo sapiens (human)	FBXL17	NP_001156787.2
Pan troglodytes (chimpanzee)	FBXL17	XP_001137158.2

Gene Ontology
Bibliography

Related articles in PubMed

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, Bristow C, Th?z?nas ML, Finta C, Christianson JC, Buffa FM, Kessler BM, Sibson NR, Di Marcotullio L, Toftg?rd R, D'Angiolella V
The EMBO journal35(13)1400-16(2016 07)

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.
Tan MK, Lim HJ, Bennett EJ, Shi Y, Harper JW
Molecular cell52(1)9-24(2013 Oct)

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA,
Proceedings of the National Academy of Sciences of the United States of America99(26)16899-903(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fbxl17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxl17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11666	NM_001108235.1 Latest version!	Rattus norvegicus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbxl17 ( NM_001108235.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101705.1 Rattus norvegicus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.

Price & Availability↑

CloneID	ORa11666
Clone ID Related Accession (Same CDS sequence)	NM_001108235.1
Accession Version	NM_001108235.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	F-box/LRR-repeat protein 17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473997.2. On or before Oct 4, 2007 this sequence version replaced XM_237458.4, XM_001071661.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGACA GTGGAGTGTG TGTTCTAGCA TTTAAGTGTC CTGGACTTCT TAGGTACACA 
GCCTACAGGT GTAAGCAGCT TTCTGACACC TCTATCATTG CGGTCGCCTC TCACTGTCCT 
TTACTGCAGA AAGTCCACGT AGGCAACCAG GACAAACTCA CTGATGAAGG ACTCAAGCAG 
CTGGGCTCAA AGTGCAGAGA ACTCAAAGAT ATTCACTTCG GCCAGTGTTA CAAGATCTCG 
GACGAAGGCA TGGTTGTCAT AGCTAAGAGC TGCCTGAAGT TGCAAAGAAT ATACATGCAG 
GAGAACAAGT TAGTGACAGA CCAGTCAGTG AAGGCCTTTG CTGAGCACTG CCCTGACCTC 
CAGTGTGTTG GCTTCATGGG TTGTTCAGTT ACTTCCAAAG GAGTCATTCA CCTAACCAAG 
CTAAGAAACC TGTCCAGCCT AGACCTGCGC CACATCACTG AACTGGACAA TGAAACTGTG 
ATGGAAATCG TCAAGAGGTG CAAAAATCTC AGCTCTCTGA ATCTCTGTCT GAACTGGATC 
ATAAACGACA GGTGTGTGGA GGTTATCGCA AAGGAGGGAC AGAGCCTGAA GGAGCTGTAC 
TTGGTGTCCT GTAAGATCAC TGACTATGCA CTGATAGCCA TTGGGCGATA CAGCGTGACC 
ATAGAGACTG TGGATGTTGG ATGGTGTAAA GAAATCACAG ATCAAGGAGC CACCCTGATT 
GCACAGAGCA GCAAGTCCCT GAGATACTTG GGCCTGATGA GATGTGATAA AGTCAACGAG 
GTAACAGTGG AGCAGCTGGT ACAGCAGTAC CCTCACATCA CCTTCAGCAC TGTCCTGCAG 
GACTGCAAGA GGACCTTGGA GAGAGCCTAC CAGATGGGCT GGACCCCCAA CATGTCCGCA 
GCCACCTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101705.1
CDS	468..1379
Translation	MSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMVVIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPDLQCVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQSLKELYLVSCKITDYALIAIGRYSVTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAATS

Target ORF information:

RefSeq Version	NM_001108235.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108235.1

ORF Insert Sequence:

ATGTCTGACA GTGGAGTGTG TGTTCTAGCA TTTAAGTGTC CTGGACTTCT TAGGTACACA 
GCCTACAGGT GTAAGCAGCT TTCTGACACC TCTATCATTG CGGTCGCCTC TCACTGTCCT 
TTACTGCAGA AAGTCCACGT AGGCAACCAG GACAAACTCA CTGATGAAGG ACTCAAGCAG 
CTGGGCTCAA AGTGCAGAGA ACTCAAAGAT ATTCACTTCG GCCAGTGTTA CAAGATCTCG 
GACGAAGGCA TGGTTGTCAT AGCTAAGAGC TGCCTGAAGT TGCAAAGAAT ATACATGCAG 
GAGAACAAGT TAGTGACAGA CCAGTCAGTG AAGGCCTTTG CTGAGCACTG CCCTGACCTC 
CAGTGTGTTG GCTTCATGGG TTGTTCAGTT ACTTCCAAAG GAGTCATTCA CCTAACCAAG 
CTAAGAAACC TGTCCAGCCT AGACCTGCGC CACATCACTG AACTGGACAA TGAAACTGTG 
ATGGAAATCG TCAAGAGGTG CAAAAATCTC AGCTCTCTGA ATCTCTGTCT GAACTGGATC 
ATAAACGACA GGTGTGTGGA GGTTATCGCA AAGGAGGGAC AGAGCCTGAA GGAGCTGTAC 
TTGGTGTCCT GTAAGATCAC TGACTATGCA CTGATAGCCA TTGGGCGATA CAGCGTGACC 
ATAGAGACTG TGGATGTTGG ATGGTGTAAA GAAATCACAG ATCAAGGAGC CACCCTGATT 
GCACAGAGCA GCAAGTCCCT GAGATACTTG GGCCTGATGA GATGTGATAA AGTCAACGAG 
GTAACAGTGG AGCAGCTGGT ACAGCAGTAC CCTCACATCA CCTTCAGCAC TGTCCTGCAG 
GACTGCAAGA GGACCTTGGA GAGAGCCTAC CAGATGGGCT GGACCCCCAA CATGTCCGCA 
GCCACCTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
The EMBO journal35(13)1400-16(2016 07)
Raducu M,Fung E,Serres S,Infante P,Barberis A,Fischer R,Bristow C,Th?z?nas ML,Finta C,Christianson JC,Buffa FM,Kessler BM,Sibson NR,Di Marcotullio L,Toftg?rd R,D'Angiolella V

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.
Molecular cell52(1)9-24(2013 Oct)
Tan MK,Lim HJ,Bennett EJ,Shi Y,Harper JW

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Proceedings of the National Academy of Sciences of the United States of America99(26)16899-903(2002 Dec)
Strausberg RL,Feingold EA,Grouse LH,Derge JG,Klausner RD,Collins FS,Wagner L,Shenmen CM,Schuler GD,Altschul SF,Zeeberg B,Buetow KH,Schaefer CF,Bhat NK,Hopkins RF,Jordan H,Moore T,Max SI,Wang J,Hsieh F,Diatchenko L,Marusina K,Farmer AA,Rubin GM,Hong L,Stapleton M,Soares MB,Bonaldo MF,Casavant TL,Scheetz TE,Brownstein MJ,Usdin TB,Toshiyuki S,Carninci P,Prange C,Raha SS,Loquellano NA,Peters GJ,Abramson RD,Mullahy SJ,Bosak SA,McEwan PJ,McKernan KJ,Malek JA,Gunaratne PH,Richards S,Worley KC,Hale S,Garcia AM,Gay LJ,Hulyk SW,Villalon DK,Muzny DM,Sodergren EJ,Lu X,Gibbs RA,Fahey J,Helton E,Ketteman M,Madan A,Rodrigues S,Sanchez A,Whiting M,Madan A,Young AC,Shevchenko Y,Bouffard GG,Blakesley RW,Touchman JW,Green ED,Dickson MC,Rodriguez AC,Grimwood J,Schmutz J,Myers RM,Butterfield YS,Krzywinski MI,Skalska U,Smailus DE,Schnerch A,Schein JE,Jones SJ,Marra MA,

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Fbxl17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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