Gene Symbol | Parn |
Entrez Gene ID | 360464 |
Full Name | poly(A)-specific ribonuclease |
Synonyms | RGD1565449 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Parn cDNA ORF clone
Gene Symbol | Parn |
Entrez Gene ID | 360464 |
Full Name | poly(A)-specific ribonuclease |
Synonyms | RGD1565449 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001270415.1 | NP_001257344.1 | poly(A)-specific ribonuclease PARN |
Homo sapiens (human) | PARN | NP_002573.1 |
Canis lupus familiaris (dog) | PARN | XP_536966.2 |
Rattus norvegicus (Norway rat) | Parn | NP_001257344.1 |
Arabidopsis thaliana (thale cress) | AHG2 | NP_175983.5 |
LOC712984 | XP_002808334.1 | |
Bos taurus (cattle) | PARN | NP_001094588.1 |
Danio rerio (zebrafish) | parn | NP_957382.1 |
Anopheles gambiae (African malaria mosquito) | PARN | XP_308433.4 |
Caenorhabditis elegans (roundworm) | K10C8.1 | NP_506169.2 |
Schizosaccharomyces pombe (fission yeast) | SPBC29A10.09c | NP_596054.1 |
Gallus gallus (chicken) | PARN | NP_001025800.1 |
Pan troglodytes (chimpanzee) | PARN | XP_510832.3 |
Mus musculus (house mouse) | Parn | NP_083037.1 |
Xenopus tropicalis (tropical clawed frog) | parn | NP_001184102.1 |
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Shukla S, Schmidt JC, Goldfarb KC, Cech TR, Parker R
Nature structural & molecular biology23(4)286-92(2016 Apr)
Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component.
Moon DH, Segal M, Boyraz B, Guinan E, Hofmann I, Cahan P, Tai AK, Agarwal S
Nature genetics47(12)1482-8(2015 Dec)
PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease.
Boele J, Persson H, Shin JW, Ishizu Y, Newie IS, S?kilde R, Hawkins SM, Coarfa C, Ikeda K, Takayama K, Horie-Inoue K, Ando Y, Burroughs AM, Sasaki C, Suzuki C, Sakai M, Aoki S, Ogawa A, Hasegawa A, Lizio M, Kaida K, Teusink B, Carninci P, Suzuki H, Inoue S, Gunaratne PH, Rovira C, Hayashizaki Y, de Hoon MJ
Proceedings of the National Academy of Sciences of the United States of America111(31)11467-72(2014 Aug)
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.
Udagawa T, Swanger SA, Takeuchi K, Kim JH, Nalavadi V, Shin J, Lorenz LJ, Zukin RS, Bassell GJ, Richter JD
Molecular cell47(2)253-66(2012 Jul)
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
poly(A) polymerase Gld2, deadenylase PARN, and translation inhibitory factor neuroguidin (Ngd) are components of a dendritic CPEB-associated polyadenylation apparatus
Title: Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.
The following Parn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Parn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa09252 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270415.1 | |
Accession Version | NM_001270415.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1875bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A)-specific ribonuclease PARN | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from HQ123458.1. On or before Jul 7, 2012 this sequence version replaced XM_001075629.3, XM_340740.5. ##Evidence-Data-START## Transcript exon combination :: HQ123458.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGAGATAA TCCGGAGCAA TTTTAAGATT AATCTTCCCA AAGTGTACCA GGCCATAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257344.1 |
CDS | 1..1875 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270415.1 |
1 | ATGGAGATAA TCCGGAGCAA TTTTAAGATT AATCTTCCCA AAGTGTACCA GGCCATAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects. |
Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component. |
PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease. |
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex. |
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. |