Spag6 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Spag6 |
| Entrez Gene ID | 360747 |
| Full Name | sperm associated antigen 6 |
| Synonyms | RGD1310892 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001034960.1 | NP_001030132.1 | sperm-associated antigen 6 |
| Homo sapiens (human) | SPAG6 | NP_036575.1 |
| Gallus gallus (chicken) | SPAG6 | NP_001186515.1 |
| Danio rerio (zebrafish) | spag6 | NP_001002210.1 |
| Xenopus tropicalis (tropical clawed frog) | spag6 | NP_001015976.1 |
| SPAG6 | XP_001097347.1 | |
| Canis lupus familiaris (dog) | SPAG6 | XP_535163.3 |
| Rattus norvegicus (Norway rat) | Spag6 | NP_001030132.1 |
| Pan troglodytes (chimpanzee) | SPAG6 | NP_001233340.1 |
| Bos taurus (cattle) | SPAG6 | NP_001033274.1 |
| Mus musculus (house mouse) | Spag6 | NP_056588.1 |
Related articles in PubMed
A heterozygous mutation disrupting the SPAG16 gene results in biochemical instability of central apparatus components of the human sperm axoneme.
Zhang Z, Zariwala MA, Mahadevan MM, Caballero-Campo P, Shen X, Escudier E, Duriez B, Bridoux AM, Leigh M, Gerton GL, Kennedy M, Amselem S, Knowles MR, Strauss JF 3rd
Biology of reproduction77(5)864-71(2007 Nov)
A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16.
Zhang Z, Sapiro R, Kapfhamer D, Bucan M, Bray J, Chennathukuzhi V, McNamara P, Curtis A, Zhang M, Blanchette-Mackie EJ, Strauss JF 3rd
Molecular and cellular biology22(22)7993-8004(2002 Nov)
Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6.
Sapiro R, Kostetskii I, Olds-Clarke P, Gerton GL, Radice GL, Strauss III JF
Molecular and cellular biology22(17)6298-305(2002 Sep)
Sperm antigen 6 is the murine homologue of the Chlamydomonas reinhardtii central apparatus protein encoded by the PF16 locus.
Sapiro R, Tarantino LM, Velazquez F, Kiriakidou M, Hecht NB, Bucan M, Strauss JF 3rd
Biology of reproduction62(3)511-8(2000 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Spag6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spag6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa09141 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001034960.1 | |
| Accession Version | NM_001034960.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | sperm-associated antigen 6 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC104678.1. On Oct 22, 2005 this sequence version replaced XM_341019.2. ##Evidence-Data-START## Transcript exon combination :: BC104678.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMEA2689595 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGAGCCAGC GGCAGGTGCT TCAAGTGTTC GAGCAGTACC AGAAAGCCCG GACGCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001030132.1 |
| CDS | 47..1570 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001034960.1 |
ORF Insert Sequence:
1 | ATGAGCCAGC GGCAGGTGCT TCAAGTGTTC GAGCAGTACC AGAAAGCCCG GACGCAATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
A heterozygous mutation disrupting the SPAG16 gene results in biochemical instability of central apparatus components of the human sperm axoneme. |
|
A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16. |
|
Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6. |
|
Sperm antigen 6 is the murine homologue of the Chlamydomonas reinhardtii central apparatus protein encoded by the PF16 locus. |