| Gene Symbol | Upf2 |
| Entrez Gene ID | 361271 |
| Full Name | UPF2, regulator of nonsense mediated mRNA decay |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Upf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Upf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa11713 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001108421.1 | |
| Accession Version | NM_001108421.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3807bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-27 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | regulator of nonsense transcripts 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473990.1. On or before Oct 4, 2007 this sequence version replaced XM_341556.3, XM_001071022.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01906348 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCCAGCTG AGCGGAAAAA GTCAGCAAGT ATGGAGGAAA AAGAATCTTT ACTAAACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101891.1 |
| CDS | 127..3933 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001108421.1 |
1 | ATGCCAGCTG AGCGGAAAAA GTCAGCAAGT ATGGAGGAAA AAGAATCTTT ACTAAACAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication. |
UPF2 is a critical regulator of liver development, function and regeneration. |
NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA. |
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. |
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. |
