Gene Symbol | Fbxl7 |
Entrez Gene ID | 361907 |
Full Name | F-box and leucine-rich repeat protein 7 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Fbxl7 cDNA ORF clone
gRNAs
Gene Symbol | Fbxl7 |
Entrez Gene ID | 361907 |
Full Name | F-box and leucine-rich repeat protein 7 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017590956.1 | XP_017446445.1 | F-box/LRR-repeat protein 7 isoform X1 |
XM_006232087.3 | XP_006232149.1 | F-box/LRR-repeat protein 7 isoform X2 |
NM_001108545.1 | NP_001102015.1 | F-box/LRR-repeat protein 7 |
XM_008760775.2 | XP_008758997.1 | F-box/LRR-repeat protein 7 isoform X2 |
XM_008760776.1 | XP_008758998.1 | F-box/LRR-repeat protein 7 isoform X2 |
XM_017590957.1 | XP_017446446.1 | F-box/LRR-repeat protein 7 isoform X2 |
FBXL7 | XP_001087468.1 | |
Canis lupus familiaris (dog) | FBXL7 | XP_005619483.1 |
Drosophila melanogaster (fruit fly) | CG4221 | NP_650512.1 |
Pan troglodytes (chimpanzee) | FBXL7 | XP_001148598.1 |
Bos taurus (cattle) | FBXL7 | XP_002696492.2 |
Gallus gallus (chicken) | FBXL7 | XP_004935160.1 |
Danio rerio (zebrafish) | zgc:158346 | NP_001073511.1 |
Homo sapiens (human) | FBXL7 | NP_036436.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003285 | XP_307793.5 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012769 | XP_306070.4 |
Mus musculus (house mouse) | Fbxl7 | NP_795933.2 |
Xenopus tropicalis (tropical clawed frog) | fbxl7 | XP_002933169.1 |
Rattus norvegicus (Norway rat) | Fbxl7 | NP_001102015.1 |
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.
Kamran M, Long ZJ, Xu D, Lv SS, Liu B, Wang CL, Xu J, Lam EW, Liu Q
Oncogenesis6(2)e298(2017 Feb)
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin.
Liu Y, Lear T, Iannone O, Shiva S, Corey C, Rajbhandari S, Jerome J, Chen BB, Mallampalli RK
The Journal of biological chemistry290(19)11843-52(2015 May)
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest.
Coon TA, Glasser JR, Mallampalli RK, Chen BB
Cell cycle (Georgetown, Tex.)11(4)721-9(2012 Feb)
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Ebstein F, Lange N, Urban S, Seifert U, Kr?ger E, Kloetzel PM
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Fbxl7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxl7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa07749 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108545.1 | |
Accession Version | NM_001108545.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473992.1. On or before Oct 4, 2007 this sequence version replaced XM_342204.3, XM_001064103.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906354 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCGCGA ACAATGGCAA ACAGTACGGC AGTGAGGGCA AGGGCAGCTC AAGCGTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102015.1 |
CDS | 464..1939 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGGCGCGA ACAATGGCAA ACAGTACGGC AGTGAGGGCA AGGGCAGCTC AAGCGTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24495 | |
Clone ID Related Accession (Same CDS sequence) | XM_006232087.3 , XM_008760775.2 , XM_008760776.1 , XM_017590957.1 | |
Accession Version | XM_006232087.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232087.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006232149.1 |
CDS | 2697..4031 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24495 | |
Clone ID Related Accession (Same CDS sequence) | XM_006232087.3 , XM_008760775.2 , XM_008760776.1 , XM_017590957.1 | |
Accession Version | XM_008760775.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760775.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008758997.1 |
CDS | 448..1782 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24495 | |
Clone ID Related Accession (Same CDS sequence) | XM_006232087.3 , XM_008760775.2 , XM_008760776.1 , XM_017590957.1 | |
Accession Version | XM_008760776.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008758998.1 |
CDS | 301..1635 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24495 | |
Clone ID Related Accession (Same CDS sequence) | XM_006232087.3 , XM_008760775.2 , XM_008760776.1 , XM_017590957.1 | |
Accession Version | XM_017590957.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017446446.1 |
CDS | 173..1507 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGCACAC TGAGCACGCC CAGCCCAGCC TTGATATGTC CACCAGCTTT GCCAGGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa59793 | |
Clone ID Related Accession (Same CDS sequence) | XM_017590956.1 | |
Accession Version | XM_017590956.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | F-box/LRR-repeat protein 7 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAATGCA GTAAGAAAAT ATACATAAGA ACACATTGGT GTATCCCCAA GCATGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017446445.1 |
CDS | 4625..6127 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAATGCA GTAAGAAAAT ATACATAAGA ACACATTGGT GTATCCCCAA GCATGCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis. |
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. |
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest. |
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. |