Gene Symbol | Flnc |
Entrez Gene ID | 362332 |
Full Name | filamin C |
Synonyms | ABP-L,FLN-C |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Flnc cDNA ORF clone
Gene Symbol | Flnc |
Entrez Gene ID | 362332 |
Full Name | filamin C |
Synonyms | ABP-L,FLN-C |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001191862.1 | NP_001178791.1 | filamin-C |
XM_006236214.3 | XP_006236276.1 | filamin-C isoform X1 |
Mus musculus (house mouse) | Flnc | NP_001074654.1 |
Canis lupus familiaris (dog) | FLNC | XP_539385.1 |
Danio rerio (zebrafish) | flnca | XP_002666982.1 |
Pan troglodytes (chimpanzee) | FLNC | XP_519364.3 |
LOC700223 | XP_002808411.1 | |
Rattus norvegicus (Norway rat) | Flnc | NP_001178791.1 |
Gallus gallus (chicken) | FLNC | NP_989904.1 |
Xenopus tropicalis (tropical clawed frog) | flnc | XP_002931884.2 |
Homo sapiens (human) | FLNC | NP_001449.3 |
Bos taurus (cattle) | FLNC | NP_001193919.1 |
Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy.
Vald?s-Mas R, Guti?rrez-Fern?ndez A, G?mez J, Coto E, Astudillo A, Puente DA, Reguero JR, ?lvarez V, Mor?s C, Le?n D, Mart?n M, Puente XS, L?pez-Ot?n C
Nature communications55326(2014 Oct)
Integrin inactivators: balancing cellular functions in vitro and in vivo.
Bouvard D, Pouwels J, De Franceschi N, Ivaska J
Nature reviews. Molecular cell biology14(7)430-42(2013 Jul)
Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.
Maiweilidan Y, Klauza I, Kordeli E
Experimental cell research317(6)724-36(2011 Apr)
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)
Nebulette interacts with filamin C.
Holmes WB, Moncman CL
Cell motility and the cytoskeleton65(2)130-42(2008 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
physical interaction between RasGAP and FLN-C facilitates an interaction between G3BP and cdk7 mRNA
Title: An alliance between Ras GTPase-activating protein, filamin C, and Ras GTPase-activating protein SH3 domain-binding protein regulates myocyte growth.
The following Flnc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Flnc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa07856 | |
Clone ID Related Accession (Same CDS sequence) | NM_001191862.1 | |
Accession Version | NM_001191862.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 8181bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | filamin-C | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07072995.1. On Jul 17, 2010 this sequence version replaced XM_342653.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689600, SAMEA2689601 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGAACA ACAGCAACTA CTCCGACGCC TCCGGCCTCG GCCTGCTTGA CGAGGCGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001178791.1 |
CDS | 190..8370 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001191862.1 |
1 | ATGATGAACA ACAGCAACTA CTCCGACGCC TCCGGCCTCG GCCTGCTTGA CGAGGCGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa27112 | |
Clone ID Related Accession (Same CDS sequence) | XM_006236214.3 | |
Accession Version | XM_006236214.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 8082bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | filamin-C isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236214.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAACA ACAGCAACTA CTCCGACGCC TCCGGCCTCG GCCTGCTTGA CGAGGCGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006236276.1 |
CDS | 342..8423 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006236214.3 |
1 | ATGATGAACA ACAGCAACTA CTCCGACGCC TCCGGCCTCG GCCTGCTTGA CGAGGCGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy. |
Integrin inactivators: balancing cellular functions in vitro and in vivo. |
Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C. |
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation. |
Nebulette interacts with filamin C. |