Gene Symbol | Derl1 |
Entrez Gene ID | 362912 |
Full Name | derlin 1 |
Synonyms | RGD1311835 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Derl1 cDNA ORF clone
Gene Symbol | Derl1 |
Entrez Gene ID | 362912 |
Full Name | derlin 1 |
Synonyms | RGD1311835 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001014202.1 | NP_001014224.1 | derlin-1 |
DERL1 | XP_001099154.1 | |
Mus musculus (house mouse) | Derl1 | NP_077169.1 |
Rattus norvegicus (Norway rat) | Derl1 | NP_001014224.1 |
Gallus gallus (chicken) | DERL1 | NP_001006350.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009288 | XP_320085.4 |
Caenorhabditis elegans (roundworm) | cup-2 | NP_492721.1 |
Xenopus tropicalis (tropical clawed frog) | derl1 | NP_001016723.1 |
Drosophila melanogaster (fruit fly) | Der-1 | NP_608632.1 |
Homo sapiens (human) | DERL1 | NP_077271.1 |
Pan troglodytes (chimpanzee) | DERL1 | XP_519933.1 |
Danio rerio (zebrafish) | derl1 | NP_998609.1 |
Canis lupus familiaris (dog) | DERL1 | XP_532320.2 |
Bos taurus (cattle) | DERL1 | NP_991358.1 |
Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
Osorio FG, Soria-Valles C, Santiago-Fern?ndez O, Bernal T, Mittelbrunn M, Colado E, Rodr?guez F, Bonzon-Kulichenko E, V?zquez J, Porta-de-la-Riva M, Cer?n J, Fueyo A, Li J, Green AR, Freije JM, L?pez-Ot?n C
Nature medicine22(1)91-6(2016 Jan)
Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP.
Kadowaki H, Nagai A, Maruyama T, Takami Y, Satrimafitrah P, Kato H, Honda A, Hatta T, Natsume T, Sato T, Kai H, Ichijo H, Nishitoh H
Cell reports13(5)944-56(2015 Nov)
Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S
Biochemical and biophysical research communications458(2)424-8(2015 Mar)
Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u.
Chen CY, Malchus NS, Hehn B, Stelzer W, Avci D, Langosch D, Lemberg MK
The EMBO journal33(21)2492-506(2014 Nov)
Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex.
Chen SF, Wu CH, Lee YM, Tam K, Tsai YC, Liou JY, Shyue SK
The Journal of biological chemistry288(46)33462-9(2013 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Derl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Derl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa05380 | |
Clone ID Related Accession (Same CDS sequence) | NM_001014202.1 | |
Accession Version | NM_001014202.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | derlin-1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085877.1. On Apr 1, 2005 this sequence version replaced XM_343242.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC085877.1, FQ218639.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCGGACA TCGGGGACTG GTTCAGGAGC ATCCCGGCCA TCACGCGCTA CTGGTTTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014224.1 |
CDS | 49..804 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001014202.1 |
1 | ATGTCGGACA TCGGGGACTG GTTCAGGAGC ATCCCGGCCA TCACGCGCTA CTGGTTTGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. |
Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP. |
Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK). |
Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u. |
Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex. |