| Gene Symbol | Meox1 |
| Entrez Gene ID | 363684 |
| Full Name | mesenchyme homeobox 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Meox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Meox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa08465 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001108837.1 | |
| Accession Version | NM_001108837.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-07-21 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | homeobox protein MOX-1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 4, 2007 this sequence version replaced XM_343970.3, XM_001081499.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001102307.1 |
| CDS | 1..762 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001108837.1 |
1 | ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa48611 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008768090.2 | |
| Accession Version | XM_008768090.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | homeobox protein MOX-1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768090.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008766312.1 |
| CDS | 519..1505 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008768090.2 |
1 | ATGGATCCGG TGGTCAACAG CTGCGTGAGG AACCCCCAGC CCCCAGCTCC CGTCTGGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling. |
Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. |
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. |
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. |
Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter. |
