Gene Symbol | Ffar3 |
Entrez Gene ID | 365228 |
Full Name | free fatty acid receptor 3 |
Synonyms | Gpr41 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ffar3 cDNA ORF clone
Gene Symbol | Ffar3 |
Entrez Gene ID | 365228 |
Full Name | free fatty acid receptor 3 |
Synonyms | Gpr41 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001108912.1 | NP_001102382.1 | free fatty acid receptor 3 |
XM_017589476.1 | XP_017444965.1 | free fatty acid receptor 3 isoform X1 |
Canis lupus familiaris (dog) | FFAR3 | XP_005616768.1 |
Pan troglodytes (chimpanzee) | FFAR3 | XP_001159667.1 |
Bos taurus (cattle) | FFAR3 | NP_001138705.1 |
Homo sapiens (human) | FFAR3 | NP_005295.1 |
FFAR3 | XP_001094758.1 | |
Mus musculus (house mouse) | Ffar3 | NP_001028488.1 |
Rattus norvegicus (Norway rat) | Ffar3 | NP_001102382.1 |
Danio rerio (zebrafish) | LOC100333904 | XP_002665089.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489919 | XP_002938262.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489751 | XP_002938261.2 |
Xenopus tropicalis (tropical clawed frog) | LOC101735161 | XP_004920890.1 |
Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon.
Kaji I, Akiba Y, Furuyama T, Adelson DW, Iwamoto K, Watanabe M, Kuwahara A, Kaunitz JD
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society30(1)(2018 Jan)
Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon.
Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD
The Journal of physiology594(12)3339-52(2016 06)
The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.
Han JH, Kim IS, Jung SH, Lee SG, Son HY, Myung CS
PloS one9(4)e95268(2014)
Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.
Kim MH, Kang SG, Park JH, Yanagisawa M, Kim CH
Gastroenterology145(2)396-406.e1-10(2013 Aug)
Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.
Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ
Proceedings of the National Academy of Sciences of the United States of America110(11)4410-5(2013 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggest that the short-chain fatty acid-FFA3 pathway has a novel anti-secretory function in that it inhibits cholinergic neural reflexes in the enteric nervous system.
Title: Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon.
The following Ffar3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ffar3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11884 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108912.1 | |
Accession Version | NM_001108912.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | free fatty acid receptor 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_344880.3, XM_001079302.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166522.1, CK603957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351, SAMN02642612 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACACAA GCTTCTTTCC CGGCAACCAC TGGCTTTTCT TTTCAGTGGA TCTGTTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102382.1 |
CDS | 64..1023 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001108912.1 |
1 | ATGGACACAA GCTTCTTTCC CGGCAACCAC TGGCTTTTCT TTTCAGTGGA TCTGTTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa56750 | |
Clone ID Related Accession (Same CDS sequence) | XM_017589476.1 | |
Accession Version | XM_017589476.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | free fatty acid receptor 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACACAG CCCTGATAAC TAGCTCAAAG CGGCTTTTGT GCAGTTCTGC AGCGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444965.1 |
CDS | 95..1240 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017589476.1 |
1 | ATGGACACAG CCCTGATAAC TAGCTCAAAG CGGCTTTTGT GCAGTTCTGC AGCGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon. |
Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. |
The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41. |
Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice. |
Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation. |