Gene Symbol | Trim72 |
Entrez Gene ID | 365377 |
Full Name | tripartite motif containing 72 |
Synonyms | RGD1562778 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Trim72 cDNA ORF clone
Gene Symbol | Trim72 |
Entrez Gene ID | 365377 |
Full Name | tripartite motif containing 72 |
Synonyms | RGD1562778 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001077675.1 | NP_001071143.1 | tripartite motif-containing protein 72 |
Pan troglodytes (chimpanzee) | TRIM72 | XP_001157628.2 |
TRIM72 | XP_001112866.1 | |
Mus musculus (house mouse) | Trim72 | NP_001073401.1 |
Rattus norvegicus (Norway rat) | Trim72 | NP_001071143.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100498595 | XP_002940825.2 |
Canis lupus familiaris (dog) | TRIM72 | XP_005621293.1 |
Bos taurus (cattle) | TRIM72 | XP_002698119.1 |
Homo sapiens (human) | TRIM72 | NP_001008275.2 |
Xenopus tropicalis (tropical clawed frog) | trim72 | NP_001008188.1 |
Potential role of MG53 in the regulation of transforming-growth-factor-?1-induced atrial fibrosis and vulnerability to atrial fibrillation.
Guo J, Jia F, Jiang Y, Li Q, Yang Y, Xiao M, Xiao H
Experimental cell research362(2)436-443(2018 Jan)
Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor.
Lemckert FA, Bournazos A, Eckert DM, Kenzler M, Hawkes JM, Butler TL, Ceely B, North KN, Winlaw DS, Egan JR, Cooper ST
Cardiovascular research110(2)178-87(2016 May)
Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet.
Qi J, Yang B, Ren C, Fu J, Zhang J
Journal of diabetes research20161564386(2016)
Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair.
Li H, Duann P, Lin PH, Zhao L, Fan Z, Tan T, Zhou X, Sun M, Fu M, Orange M, Sermersheim M, Ma H, He D, Steinberg SM, Higgins R, Zhu H, John E, Zeng C, Guan J, Ma J
The Journal of biological chemistry290(40)24592-603(2015 Oct)
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling.
Yi JS, Park JS, Ham YM, Nguyen N, Lee NR, Hong J, Kim BW, Lee H, Lee CS, Jeong BC, Song HK, Cho H, Kim YK, Lee JS, Park KS, Shin H, Choi I, Lee SH, Park WJ, Park SY, Choi CS, Lin P, Karunasiri M, Tan T, Duann P, Zhu H, Ma J, Ko YG
Nature communications42354(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
MG53 is an effective biomarker of myocardial injury and dysfunction in murine hearts. However, MG53 is not expressed in human heart and therefore does not hold utility as a clinical biomarker of myocardial injury
Title: Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor.
These results suggest that an 8-week swimming exercise improves HFD-induced insulin resistance maybe through a reduction of TRIM72 in skeletal muscle and enhancement of AKT signal transduction.
Title: Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet.
MG53 is a facilitator of rapid injury repair, a mediator of cell migration, and a modulator of myofibroblast differentiation during wound healing
Title: Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair.
MG53, a member of the muscle-specific transmembrane adaptor molecule (TRIM) protein family, is a crucial component of the cardiac ischemic preconditioning response.
Title: MG53 constitutes a primary determinant of cardiac ischemic preconditioning.
The following Trim72 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trim72 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10400 | |
Clone ID Related Accession (Same CDS sequence) | NM_001077675.1 | |
Accession Version | NM_001077675.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tripartite motif-containing protein 72 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC127539.1. On or before Nov 15, 2006 this sequence version replaced XM_344967.3, XM_001080388.1. ##Evidence-Data-START## Transcript exon combination :: BC127539.1, FQ224850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689596, SAMEA2689600 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCGACTG CACCAGGCCT TTTGCGCCAG GAACTGTCTT GCCCGCTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001071143.1 |
CDS | 89..1522 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001077675.1 |
1 | ATGTCGACTG CACCAGGCCT TTTGCGCCAG GAACTGTCTT GCCCGCTGTG CTTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Potential role of MG53 in the regulation of transforming-growth-factor-?1-induced atrial fibrosis and vulnerability to atrial fibrillation. |
Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. |
Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet. |
Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair. |
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling. |