Gene Symbol | Lzts2 |
Entrez Gene ID | 365468 |
Full Name | leucine zipper tumor suppressor 2 |
Synonyms | Lapser1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Lzts2 cDNA ORF clone
gRNAs
Gene Symbol | Lzts2 |
Entrez Gene ID | 365468 |
Full Name | leucine zipper tumor suppressor 2 |
Synonyms | Lapser1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006231549.3 | XP_006231611.1 | leucine zipper putative tumor suppressor 2 isoform X1 |
XM_017589509.1 | XP_017444998.1 | leucine zipper putative tumor suppressor 2 isoform X1 |
XM_017589508.1 | XP_017444997.1 | leucine zipper putative tumor suppressor 2 isoform X1 |
XM_017589510.1 | XP_017444999.1 | leucine zipper putative tumor suppressor 2 isoform X1 |
NM_001014247.2 | NP_001014269.2 | leucine zipper putative tumor suppressor 2 |
XM_006231547.3 | XP_006231609.1 | leucine zipper putative tumor suppressor 2 isoform X1 |
Homo sapiens (human) | LZTS2 | NP_115805.1 |
Canis lupus familiaris (dog) | LZTS2 | XP_005637688.1 |
Pan troglodytes (chimpanzee) | LZTS2 | XP_001169360.1 |
Gallus gallus (chicken) | LZTS2 | XP_426530.4 |
Danio rerio (zebrafish) | lzts2a | NP_001139078.1 |
LZTS2 | XP_001109817.1 | |
Bos taurus (cattle) | LZTS2 | NP_001092332.1 |
Rattus norvegicus (Norway rat) | Lzts2 | NP_001014269.2 |
Mus musculus (house mouse) | Lzts2 | NP_663478.2 |
Xenopus tropicalis (tropical clawed frog) | lzts2 | NP_001006721.1 |
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)
Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development.
Johnson DT, Luong R, Lee SH, Peng Y, Shaltouki A, Lee JT, Lin D, Wang Y, Sun Z
The Journal of biological chemistry288(6)3727-38(2013 Feb)
The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.
Peng Y, Clark C, Luong R, Tu WH, Lee J, Johnson DT, Das A, Carroll TJ, Sun Z
The Journal of biological chemistry286(46)40331-42(2011 Nov)
Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses.
Schmeisser MJ, Grabrucker AM, Bockmann J, Boeckers TM
The Journal of biological chemistry284(42)29146-57(2009 Oct)
LAPSER1 is a putative cytokinetic tumor suppressor that shows the same centrosome and midbody subcellular localization pattern as p80 katanin.
Sudo H, Maru Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology21(9)2086-100(2007 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
analysis of cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses
Title: Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses.
LAPSER1 localizes to the centrosomes & midbodies in mitotic cells. LAPSER1 participates in cytokinesis by interacting with p80 katanin, the disruption of which may potentially cause genetic instability and cancer.
Title: LAPSER1 is a putative cytokinetic tumor suppressor that shows the same centrosome and midbody subcellular localization pattern as p80 katanin.
The following Lzts2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lzts2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | NM_001014247.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-21 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC083580.1, DQ176638.2 and DN932851.1. On Oct 16, 2009 this sequence version replaced NM_001014247.1. ##Evidence-Data-START## Transcript exon combination :: AY928801.1, DQ176638.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014269.2 |
CDS | 43..2055 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | XM_006231549.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231549.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006231611.1 |
CDS | 1522..3534 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | XM_017589509.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444998.1 |
CDS | 173..2185 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | XM_017589508.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444997.1 |
CDS | 183..2195 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | XM_017589510.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444999.1 |
CDS | 220..2232 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05506 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231549.3 , XM_017589509.1 , XM_017589508.1 , XM_017589510.1 , NM_001014247.2 , XM_006231547.3 | |
Accession Version | XM_006231547.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | leucine zipper putative tumor suppressor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231547.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006231609.1 |
CDS | 717..2729 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCATTG TGCACACTCT GCCAGTGCCA CTGGAGCCCG CACGTGAGAC AGCCACTGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics. |
Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development. |
The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development. |
Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses. |
LAPSER1 is a putative cytokinetic tumor suppressor that shows the same centrosome and midbody subcellular localization pattern as p80 katanin. |