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Nrarp cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Nrarp
Entrez Gene ID 499745
Full Name Notch-regulated ankyrin repeat protein
General protein information
Preferred Names

Notch-regulated ankyrin repeat protein

Names

notch-regulated ankyrin repeat-containing protein
Maternal Effect Lethal family member (mel-11)-like
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3p13

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001143750.1 NP_001137222.1 notch-regulated ankyrin repeat-containing protein
XM_017601817.1 XP_017457306.1 notch-regulated ankyrin repeat-containing protein isoform X1

Pathways from BioSystems


Homologies


LOC720929 XP_001116892.1
Rattus norvegicus (Norway rat) Nrarp NP_001137222.1
Danio rerio (zebrafish) nrarpa NP_852472.1
Homo sapiens (human) NRARP NP_001004354.1
Pan troglodytes (chimpanzee) NRARP XP_528519.1
Gallus gallus (chicken) NRARP XP_428951.2
Canis lupus familiaris (dog) NRARP XP_005625115.1
Bos taurus (cattle) NRARP XP_005213553.1
Mus musculus (house mouse) Nrarp NP_080256.2

Gene Ontology


Bibliography

Related articles in PubMed

C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.
Zhu P, Wang Y, Du Y, He L, Huang G, Zhang G, Yan X, Fan Z
Nature communications67122(2015 May)

Mir-181b Functions as Anti-Apoptotic Gene in Post-Status Epilepticus via Modulation of Nrarp and Notch Signaling Pathway.
Zhang C, Hou D, Feng X
Annals of clinical and laboratory science45(5)550-5(2015)

The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.
Krebs LT, Bradley CK, Norton CR, Xu J, Oram KF, Starling C, Deftos ML, Bevan MJ, Gridley T
Genesis (New York, N.Y. : 2000)50(4)366-74(2012 Apr)

The period of the somite segmentation clock is sensitive to Notch activity.
Kim W, Matsui T, Yamao M, Ishibashi M, Tamada K, Takumi T, Kohno K, Oba S, Ishii S, Sakumura Y, Bessho Y
Molecular biology of the cell22(18)3541-9(2011 Sep)

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Phng LK, Potente M, Leslie JD, Babbage J, Nyqvist D, Lobov I, Ondr JK, Rao S, Lang RA, Thurston G, Gerhardt H
Developmental cell16(1)70-82(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MiR-181b negatively regulated Nrarp as an anti-apoptotic gene via Notch signaling pathway in hippocampus.
Title: Mir-181b Functions as Anti-Apoptotic Gene in Post-Status Epilepticus via Modulation of Nrarp and Notch Signaling Pathway.

The following Nrarp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nrarp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa12727 NM_001143750.1
Latest version!		 Rattus norvegicus Notch-regulated ankyrin repeat protein (Nrarp), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
ORa12727 XM_017601817.1
Latest version!		 Rattus norvegicus Notch-regulated ankyrin repeat protein (Nrarp), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa12727
Clone ID Related Accession (Same CDS sequence) NM_001143750.1 , XM_017601817.1
Accession Version NM_001143750.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 345bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-05-27
Organism Rattus norvegicus(Norway rat)
Product notch-regulated ankyrin repeat-containing protein
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07051240.1. On or before Apr 11, 2014 this sequence version replaced XM_006227200.1, XM_001077307.1, XM_575080.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. 

1
61
121
181
241
301
ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA 
GCGGTGCGCA AGGGCAACAC ACAGGAGCTT CAGTCGCTGC TGCAGAACAT GACTAACTGC 
GAATTCAACG TGAACTCGTT CGGGCCGGAG GGCCAGACAG CACTACACCA GTCAGTCATC 
GACGGCAACC TGGAGCTGGT GAAGCTGCTA GTCAAATTCG GCGCAGACAT CCGCCTAGCC 
AACCGCGACG GCTGGAGCGC ACTGCACATC GCCGCTTTCG GGGGCCACCA GGACATCGTG 
CTCTATCTCA TCACCAAGGC CAAGTACGCG GCCAGCGGCC GGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001137222.1
CDS354..698
Translation

Target ORF information:

RefSeq Version NM_001143750.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus Notch-regulated ankyrin repeat protein (Nrarp), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001143750.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA 
GCGGTGCGCA AGGGCAACAC ACAGGAGCTT CAGTCGCTGC TGCAGAACAT GACTAACTGC 
GAATTCAACG TGAACTCGTT CGGGCCGGAG GGCCAGACAG CACTACACCA GTCAGTCATC 
GACGGCAACC TGGAGCTGGT GAAGCTGCTA GTCAAATTCG GCGCAGACAT CCGCCTAGCC 
AACCGCGACG GCTGGAGCGC ACTGCACATC GCCGCTTTCG GGGGCCACCA GGACATCGTG 
CTCTATCTCA TCACCAAGGC CAAGTACGCG GCCAGCGGCC GGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa12727
Clone ID Related Accession (Same CDS sequence) NM_001143750.1 , XM_017601817.1
Accession Version XM_017601817.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 345bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product notch-regulated ankyrin repeat-containing protein isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000071.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA 
GCGGTGCGCA AGGGCAACAC ACAGGAGCTT CAGTCGCTGC TGCAGAACAT GACTAACTGC 
GAATTCAACG TGAACTCGTT CGGGCCGGAG GGCCAGACAG CACTACACCA GTCAGTCATC 
GACGGCAACC TGGAGCTGGT GAAGCTGCTA GTCAAATTCG GCGCAGACAT CCGCCTAGCC 
AACCGCGACG GCTGGAGCGC ACTGCACATC GCCGCTTTCG GGGGCCACCA GGACATCGTG 
CTCTATCTCA TCACCAAGGC CAAGTACGCG GCCAGCGGCC GGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017457306.1
CDS445..789
Translation

Target ORF information:

RefSeq Version XM_017601817.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus Notch-regulated ankyrin repeat protein (Nrarp), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017601817.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGAGCCAAG CCGAGCTGTC CACCTGCTCG GCGCCACAGA CGCAGCGCAT CTTCCAGGAA 
GCGGTGCGCA AGGGCAACAC ACAGGAGCTT CAGTCGCTGC TGCAGAACAT GACTAACTGC 
GAATTCAACG TGAACTCGTT CGGGCCGGAG GGCCAGACAG CACTACACCA GTCAGTCATC 
GACGGCAACC TGGAGCTGGT GAAGCTGCTA GTCAAATTCG GCGCAGACAT CCGCCTAGCC 
AACCGCGACG GCTGGAGCGC ACTGCACATC GCCGCTTTCG GGGGCCACCA GGACATCGTG 
CTCTATCTCA TCACCAAGGC CAAGTACGCG GCCAGCGGCC GGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.
Nature communications67122(2015 May)
Zhu P,Wang Y,Du Y,He L,Huang G,Zhang G,Yan X,Fan Z


book

Mir-181b Functions as Anti-Apoptotic Gene in Post-Status Epilepticus via Modulation of Nrarp and Notch Signaling Pathway.
Annals of clinical and laboratory science45(5)550-5(2015)
Zhang C,Hou D,Feng X


book

The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.
Genesis (New York, N.Y. : 2000)50(4)366-74(2012 Apr)
Krebs LT,Bradley CK,Norton CR,Xu J,Oram KF,Starling C,Deftos ML,Bevan MJ,Gridley T


book

The period of the somite segmentation clock is sensitive to Notch activity.
Molecular biology of the cell22(18)3541-9(2011 Sep)
Kim W,Matsui T,Yamao M,Ishibashi M,Tamada K,Takumi T,Kohno K,Oba S,Ishii S,Sakumura Y,Bessho Y


book

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Developmental cell16(1)70-82(2009 Jan)
Phng LK,Potente M,Leslie JD,Babbage J,Nyqvist D,Lobov I,Ondr JK,Rao S,Lang RA,Thurston G,Gerhardt H