| Gene Symbol | Tprn |
| Entrez Gene ID | 499749 |
| Full Name | taperin |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Tprn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tprn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa06304 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001024309.2 | |
| Accession Version | NM_001024309.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-18 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | taperin | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07051240.1 and BC083928.1. On Jun 11, 2008 this sequence version replaced NM_001024309.1. Sequence Note: This RefSeq record was created from transcript and genomic data because transcript data was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by orthologous data from mouse RefSeq NM_175286. ##Evidence-Data-START## Transcript exon combination :: BC083928.1, FM060402.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCGGCC TGGGGCGGCT CGATCCGGGG CCGCGAACCG TGATGCCCGC CTGGAAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001019480.2 |
| CDS | 1..2262 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001024309.2 |
1 | ATGGCCGGCC TGGGGCGGCT CGATCCGGGG CCGCGAACCG TGATGCCCGC CTGGAAACGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Progressive hearing loss and degeneration of hair cell stereocilia in taperin gene knockout mice. |
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. |
Mutations in TPRN cause a progressive form of autosomal-recessive nonsyndromic hearing loss. |
Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79. |
