Gene Symbol | Esco1 |
Entrez Gene ID | 680014 |
Full Name | establishment of sister chromatid cohesion N-acetyltransferase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Esco1 cDNA ORF clone
gRNAs
Gene Symbol | Esco1 |
Entrez Gene ID | 680014 |
Full Name | establishment of sister chromatid cohesion N-acetyltransferase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006254415.3 | XP_006254477.1 | N-acetyltransferase ESCO1 isoform X2 |
XM_006254412.3 | XP_006254474.1 | N-acetyltransferase ESCO1 isoform X1 |
XM_017601036.1 | XP_017456525.1 | N-acetyltransferase ESCO1 isoform X1 |
XM_017601037.1 | XP_017456526.1 | N-acetyltransferase ESCO1 isoform X1 |
NM_001126299.2 | NP_001119771.2 | N-acetyltransferase ESCO1 |
Canis lupus familiaris (dog) | ESCO1 | XP_005623075.1 |
Rattus norvegicus (Norway rat) | RGD1562794 | XP_003751278.1 |
Gallus gallus (chicken) | ESCO1 | XP_004939821.1 |
Bos taurus (cattle) | ESCO1 | XP_005224156.1 |
Rattus norvegicus (Norway rat) | Esco1 | NP_001119771.2 |
Homo sapiens (human) | ESCO1 | NP_443143.2 |
Mus musculus (house mouse) | Esco1 | NP_001074691.1 |
Pan troglodytes (chimpanzee) | ESCO1 | XP_523883.3 |
ESCO1 | XP_001091733.1 |
Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1.
Rivera-Col?n Y, Maguire A, Liszczak GP, Olia AS, Marmorstein R
The Journal of biological chemistry291(51)26468-26477(2016 Dec)
Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.
Kouznetsova E, Kanno T, Karlberg T, Thorsell AG, Wisniewska M, Kursula P, Sj?gren C, Sch?ler H
Structure (London, England : 1993)24(5)789-796(2016 05)
Sororin mediates sister chromatid cohesion by antagonizing Wapl.
Nishiyama T, Ladurner R, Schmitz J, Kreidl E, Schleiffer A, Bhaskara V, Bando M, Shirahige K, Hyman AA, Mechtler K, Peters JM
Cell143(5)737-49(2010 Nov)
Cohesin acetylation speeds the replication fork.
Terret ME, Sherwood R, Rahman S, Qin J, Jallepalli PV
Nature462(7270)231-4(2009 Nov)
Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion.
Hou F, Zou H
Molecular biology of the cell16(8)3908-18(2005 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Esco1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Esco1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01385 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254412.3 , XM_017601036.1 , XM_017601037.1 , NM_001126299.2 | |
Accession Version | NM_001126299.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-acetyltransferase ESCO1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC166441.1. On Dec 1, 2010 this sequence version replaced NM_001126299.1. ##Evidence-Data-START## Transcript exon combination :: BC166441.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001119771.2 |
CDS | 468..2990 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa01385 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254412.3 , XM_017601036.1 , XM_017601037.1 , NM_001126299.2 | |
Accession Version | XM_006254412.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-acetyltransferase ESCO1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254412.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006254474.1 |
CDS | 1244..3766 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa01385 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254412.3 , XM_017601036.1 , XM_017601037.1 , NM_001126299.2 | |
Accession Version | XM_017601036.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-acetyltransferase ESCO1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017456525.1 |
CDS | 1019..3541 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa01385 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254412.3 , XM_017601036.1 , XM_017601037.1 , NM_001126299.2 | |
Accession Version | XM_017601037.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-acetyltransferase ESCO1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017456526.1 |
CDS | 1286..3808 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa38180 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254415.3 | |
Accession Version | XM_006254415.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2025bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | N-acetyltransferase ESCO1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254415.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006254477.1 |
CDS | 1246..3270 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCCATTC AGGAGAAATC AAAAGAAAAT TCCTCCAAAG TTATTAAAGA AAGTGAAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. |
Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis. |
Sororin mediates sister chromatid cohesion by antagonizing Wapl. |
Cohesin acetylation speeds the replication fork. |
Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion. |