Nme4 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Nme4 |
| Entrez Gene ID | 685679 |
| Full Name | NME/NM23 nucleoside diphosphate kinase 4 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001109478.1 | NP_001102948.1 | nucleoside diphosphate kinase, mitochondrial |
| Canis lupus familiaris (dog) | NME4 | XP_005642532.1 |
| Rattus norvegicus (Norway rat) | Nme4 | NP_001102948.1 |
| Homo sapiens (human) | NME4 | NP_005000.1 |
| Mus musculus (house mouse) | Nme4 | NP_062705.1 |
| Pan troglodytes (chimpanzee) | NME4 | XP_003314942.2 |
| Canis lupus familiaris (dog) | LOC102151128 | XP_005633907.1 |
| Danio rerio (zebrafish) | nme4 | NP_957489.1 |
| Xenopus tropicalis (tropical clawed frog) | nme4 | NP_001039239.1 |
Related articles in PubMed
Metabolism and function of mitochondrial cardiolipin.
Ren M, Phoon CK, Schlame M
Progress in lipid research551-16(2014 Jul)
Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch.
Schlattner U, Tokarska-Schlattner M, Ramirez S, Tyurina YY, Amoscato AA, Mohammadyani D, Huang Z, Jiang J, Yanamala N, Seffouh A, Boissan M, Epand RF, Epand RM, Klein-Seetharaman J, Lacombe ML, Kagan VE
The Journal of biological chemistry288(1)111-21(2013 Jan)
The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration.
Tokarska-Schlattner M, Boissan M, Munier A, Borot C, Mailleau C, Speer O, Schlattner U, Lacombe ML
The Journal of biological chemistry283(38)26198-207(2008 Sep)
Identification and analysis of plasticity-induced late-response genes.
Hong SJ, Li H, Becker KG, Dawson VL, Dawson TM
Proceedings of the National Academy of Sciences of the United States of America101(7)2145-50(2004 Feb)
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Nm23-H4 acts as a lipid-dependent mitochondrial switch with dual function in phosphotransfer serving local GTP supply and cardiolipin transfer for apoptotic signaling and putative other functions
Title: Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch.
NM23-H4 binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration
Title: The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration.
The following Nme4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nme4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa10058 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001109478.1 | |
| Accession Version | NM_001109478.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | nucleoside diphosphate kinase, mitochondrial | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On Oct 4, 2007 this sequence version replaced XM_001064805.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## | |
1 | ATGGGTTGCT TGTTCGATCG CGCCGCGCTG CGGGCGCTGT TGTGCGGGCC ACGCTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001102948.1 |
| CDS | 19..576 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001109478.1 |
ORF Insert Sequence:
1 | ATGGGTTGCT TGTTCGATCG CGCCGCGCTG CGGGCGCTGT TGTGCGGGCC ACGCTTTCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Metabolism and function of mitochondrial cardiolipin. |
|
Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. |
|
The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration. |
|
Identification and analysis of plasticity-induced late-response genes. |
|
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |