Srsf1 cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Srsf1 |
Entrez Gene ID | 689890 |
Full Name | serine and arginine rich splicing factor 1 |
Synonyms | Sfrs1 |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
XM_008768114.2 | XP_008766336.1 | serine/arginine-rich splicing factor 1 isoform X1 |
NM_001109552.2 | NP_001103022.1 | serine/arginine-rich splicing factor 1 |

Pan troglodytes (chimpanzee) | SRSF1 | NP_001182476.1 |
Gallus gallus (chicken) | SRSF1 | NP_001107213.1 |
Xenopus tropicalis (tropical clawed frog) | srsf1 | NP_001006919.1 |
Homo sapiens (human) | SRSF1 | NP_008855.1 |
Danio rerio (zebrafish) | srsf1a | NP_998180.1 |
Drosophila melanogaster (fruit fly) | SF2 | NP_652611.1 |
Mus musculus (house mouse) | Srsf1 | NP_775550.2 |
Arabidopsis thaliana (thale cress) | SR1 | NP_850934.1 |
Canis lupus familiaris (dog) | SRSF1 | XP_005624772.1 |
Bos taurus (cattle) | SRSF1 | NP_001069862.1 |
SRSF1 | XP_001103473.2 | |
Rattus norvegicus (Norway rat) | Srsf1 | NP_001103022.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010496 | XP_314469.4 |
Caenorhabditis elegans (roundworm) | rsp-3 | NP_499649.2 |
Arabidopsis thaliana (thale cress) | AT4G02430 | NP_567235.3 |

Related articles in PubMed
SRSF1 promotes vascular smooth muscle cell proliferation through a ?133p53/EGR1/KLF5 pathway.
Xie N, Chen M, Dai R, Zhang Y, Zhao H, Song Z, Zhang L, Li Z, Feng Y, Gao H, Wang L, Zhang T, Xiao RP, Wu J, Cao CM
Nature communications816016(2017 Aug)
Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors.
Chettouh H, Fartoux L, Aoudjehane L, Wendum D, Clap?ron A, Chr?tien Y, Rey C, Scatton O, Soubrane O, Conti F, Praz F, Housset C, Rosmorduc O, Desbois-Mouthon C
Cancer research73(13)3974-86(2013 Jul)
Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact.
Iborra S, Hirschfeld M, Jaeger M, Zur Hausen A, Braicu I, Sehouli J, Gitsch G, Stickeler E
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society23(6)990-6(2013 Jul)
Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF.
Piekielko-Witkowska A, Kedzierska H, Poplawski P, Wojcicka A, Rybicka B, Maksymowicz M, Grajkowska W, Matyja E, Mandat T, Bonicki W, Nauman P
Biochimica et biophysica acta1832(6)763-72(2013 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a new mechanism of posttranscriptional regulation of DIO1 and show deregulation of DIO1 expression in pituitary adenoma, possibly resulting from disturbed expression of SF2/ASF.
Title: Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF.
The following Srsf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srsf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10307 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109552.2 | |
Accession Version | NM_001109552.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
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Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-22 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | serine/arginine-rich splicing factor 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030193.1, FM051934.1 and FM055064.1. On Sep 11, 2010 this sequence version replaced NM_001109552.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CO567930.1, EV774551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCAGGAG GTGGTGTGAT TCGTGGCCCG GCAGGGAACA ACGACTGCCG CATCTACGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001103022.1 |
CDS | 125..871 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGTCAGGAG GTGGTGTGAT TCGTGGCCCG GCAGGGAACA ACGACTGCCG CATCTACGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa50407 | |
Clone ID Related Accession (Same CDS sequence) | XM_008768114.2 | |
Accession Version | XM_008768114.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | serine/arginine-rich splicing factor 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768114.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGGAAG GAGGGGCTCC GAGGCTGGGA GCGAGGCGCT ATCGCCCCTG CAGGAGTCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008766336.1 |
CDS | 1340..2236 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGGGGAAG GAGGGGCTCC GAGGCTGGGA GCGAGGCGCT ATCGCCCCTG CAGGAGTCGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
SRSF1 promotes vascular smooth muscle cell proliferation through a ?133p53/EGR1/KLF5 pathway. |
![]() |
Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors. |
![]() |
Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact. |
![]() |
Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF. |