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Srsf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Srsf1
Entrez Gene ID 689890
Full Name serine and arginine rich splicing factor 1
Synonyms Sfrs1
General protein information
Preferred Names

serine and arginine rich splicing factor 1

Names

serine/arginine-rich splicing factor 1
splicing factor, arginine/serine-rich 1
splicing factor, arginine/serine-rich 1B
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

10

10q26

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_008768114.2 XP_008766336.1 serine/arginine-rich splicing factor 1 isoform X1
NM_001109552.2 NP_001103022.1 serine/arginine-rich splicing factor 1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) SRSF1 NP_001182476.1
Gallus gallus (chicken) SRSF1 NP_001107213.1
Xenopus tropicalis (tropical clawed frog) srsf1 NP_001006919.1
Homo sapiens (human) SRSF1 NP_008855.1
Danio rerio (zebrafish) srsf1a NP_998180.1
Drosophila melanogaster (fruit fly) SF2 NP_652611.1
Mus musculus (house mouse) Srsf1 NP_775550.2
Arabidopsis thaliana (thale cress) SR1 NP_850934.1
Canis lupus familiaris (dog) SRSF1 XP_005624772.1
Bos taurus (cattle) SRSF1 NP_001069862.1
SRSF1 XP_001103473.2
Rattus norvegicus (Norway rat) Srsf1 NP_001103022.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP010496 XP_314469.4
Caenorhabditis elegans (roundworm) rsp-3 NP_499649.2
Arabidopsis thaliana (thale cress) AT4G02430 NP_567235.3

Gene Ontology


Bibliography

Related articles in PubMed

SRSF1 promotes vascular smooth muscle cell proliferation through a ?133p53/EGR1/KLF5 pathway.
Xie N, Chen M, Dai R, Zhang Y, Zhao H, Song Z, Zhang L, Li Z, Feng Y, Gao H, Wang L, Zhang T, Xiao RP, Wu J, Cao CM
Nature communications816016(2017 Aug)

Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors.
Chettouh H, Fartoux L, Aoudjehane L, Wendum D, Clap?ron A, Chr?tien Y, Rey C, Scatton O, Soubrane O, Conti F, Praz F, Housset C, Rosmorduc O, Desbois-Mouthon C
Cancer research73(13)3974-86(2013 Jul)

Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact.
Iborra S, Hirschfeld M, Jaeger M, Zur Hausen A, Braicu I, Sehouli J, Gitsch G, Stickeler E
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society23(6)990-6(2013 Jul)

Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF.
Piekielko-Witkowska A, Kedzierska H, Poplawski P, Wojcicka A, Rybicka B, Maksymowicz M, Grajkowska W, Matyja E, Mandat T, Bonicki W, Nauman P
Biochimica et biophysica acta1832(6)763-72(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Srsf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srsf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa10307 NM_001109552.2
Latest version!		 Rattus norvegicus serine and arginine rich splicing factor 1 (Srsf1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
ORa50407 XM_008768114.2
Latest version!		 Rattus norvegicus serine and arginine rich splicing factor 1 (Srsf1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa10307
Clone ID Related Accession (Same CDS sequence) NM_001109552.2
Accession Version NM_001109552.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-12-22
Organism Rattus norvegicus(Norway rat)
Product serine/arginine-rich splicing factor 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07030193.1, FM051934.1 and FM055064.1. On Sep 11, 2010 this sequence version replaced NM_001109552.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CO567930.1, EV774551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCAGGAG GTGGTGTGAT TCGTGGCCCG GCAGGGAACA ACGACTGCCG CATCTACGTG 
GGTAACCTAC CTCCAGACAT CCGAACCAAG GACATTGAGG ACGTGTTTTA CAAATACGGC 
GCTATCCGCG ACATCGACCT GAAGAACCGC CGCGGGGGAC CGCCCTTCGC CTTCGTTGAG 
TTCGAGGACC CGCGAGACGC GGAAGATGCG GTGTACGGTC GCGACGGCTA CGATTACGAC 
GGCTACCGTC TGCGGGTAGA GTTTCCCCGA AGCGGCCGTG GGACCGGCCG AGGCGGCGGC 
GGGGGTGGAG GCGGCGGAGC CCCGAGAGGC CGCTATGGCC CGCCATCCAG GCGGTCTGAA 
AACAGAGTGG TTGTTTCTGG ACTGCCTCCG AGTGGAAGCT GGCAGGACTT AAAGGATCAC 
ATGCGTGAAG CAGGTGATGT ATGTTATGCT GATGTTTACC GAGATGGCAC TGGTGTCGTG 
GAGTTTGTAC GGAAAGAAGA TATGACGTAT GCAGTTCGAA AACTGGATAA CACTAAGTTT 
AGATCTCATG AGGGAGAAAC TGCCTACATC CGGGTTAAAG TTGATGGGCC CAGAAGTCCA 
AGTTATGGAA GATCTCGATC TCGAAGCCGT AGTCGTAGCA GAAGCCGTAG CAGAAGCAAC 
AGCAGGAGTC GCAGTTACTC CCCAAGGAGA AGCAGAGGAT CACCACGCTA TTCTCCCCGT 
CATAGCAGAT CTCGCTCTCG TACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001103022.1
CDS125..871
Translation

Target ORF information:

RefSeq Version NM_001109552.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus serine and arginine rich splicing factor 1 (Srsf1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001109552.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCAGGAG GTGGTGTGAT TCGTGGCCCG GCAGGGAACA ACGACTGCCG CATCTACGTG 
GGTAACCTAC CTCCAGACAT CCGAACCAAG GACATTGAGG ACGTGTTTTA CAAATACGGC 
GCTATCCGCG ACATCGACCT GAAGAACCGC CGCGGGGGAC CGCCCTTCGC CTTCGTTGAG 
TTCGAGGACC CGCGAGACGC GGAAGATGCG GTGTACGGTC GCGACGGCTA CGATTACGAC 
GGCTACCGTC TGCGGGTAGA GTTTCCCCGA AGCGGCCGTG GGACCGGCCG AGGCGGCGGC 
GGGGGTGGAG GCGGCGGAGC CCCGAGAGGC CGCTATGGCC CGCCATCCAG GCGGTCTGAA 
AACAGAGTGG TTGTTTCTGG ACTGCCTCCG AGTGGAAGCT GGCAGGACTT AAAGGATCAC 
ATGCGTGAAG CAGGTGATGT ATGTTATGCT GATGTTTACC GAGATGGCAC TGGTGTCGTG 
GAGTTTGTAC GGAAAGAAGA TATGACGTAT GCAGTTCGAA AACTGGATAA CACTAAGTTT 
AGATCTCATG AGGGAGAAAC TGCCTACATC CGGGTTAAAG TTGATGGGCC CAGAAGTCCA 
AGTTATGGAA GATCTCGATC TCGAAGCCGT AGTCGTAGCA GAAGCCGTAG CAGAAGCAAC 
AGCAGGAGTC GCAGTTACTC CCCAAGGAGA AGCAGAGGAT CACCACGCTA TTCTCCCCGT 
CATAGCAGAT CTCGCTCTCG TACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa50407
Clone ID Related Accession (Same CDS sequence) XM_008768114.2
Accession Version XM_008768114.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 897bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product serine/arginine-rich splicing factor 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768114.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGGGGAAG GAGGGGCTCC GAGGCTGGGA GCGAGGCGCT ATCGCCCCTG CAGGAGTCGA 
GTAAGGAGCC GAGTCGGCGC GTTGTCTCCG GTGGCTGACC GCCTCGGACG TCCCCAGAGC 
CCATGCGCAG CCCCGGAGCG GGAAACTGAG GCGCTGAGGG CTGGCGTGGT GGTCGGGAGT 
CTGCCCGGCG TGTTTCTGGG TGGGGGAGGG GCCGGTCCTA TTATGCAGCG CATGTGGGCT 
CTGGCACCAT GGGTGCGCAT GTGCGCTGTC CGCGGGTTCC CGAGTGAGTT AGCTTTGCCA 
GCGGCTCCCT CCTCATCCCC TTTGCTTTCT GTGATCACAC GCAGAGACGC GGAAGATGCG 
GTGTACGGTC GCGACGGCTA CGATTACGAC GGCTACCGTC TGCGGGTAGA GTTTCCCCGA 
AGCGGCCGTG GGACCGGCCG AGGCGGCGGC GGGGGTGGAG GCGGCGGAGC CCCGAGAGGC 
CGCTATGGCC CGCCATCCAG GCGGTCTGAA AACAGAGTGG TTGTTTCTGG ACTGCCTCCG 
AGTGGAAGCT GGCAGGACTT AAAGGATCAC ATGCGTGAAG CAGGTGATGT ATGTTATGCT 
GATGTTTACC GAGATGGCAC TGGTGTCGTG GAGTTTGTAC GGAAAGAAGA TATGACGTAT 
GCAGTTCGAA AACTGGATAA CACTAAGTTT AGATCTCATG AGGGAGAAAC TGCCTACATC 
CGGGTTAAAG TTGATGGGCC CAGAAGTCCA AGTTATGGAA GATCTCGATC TCGAAGCCGT 
AGTCGTAGCA GAAGCCGTAG CAGAAGCAAC AGCAGGAGTC GCAGTTACTC CCCAAGGAGA 
AGCAGAGGAT CACCACGCTA TTCTCCCCGT CATAGCAGAT CTCGCTCTCG TACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008766336.1
CDS1340..2236
Translation

Target ORF information:

RefSeq Version XM_008768114.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus serine and arginine rich splicing factor 1 (Srsf1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008768114.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGGGGAAG GAGGGGCTCC GAGGCTGGGA GCGAGGCGCT ATCGCCCCTG CAGGAGTCGA 
GTAAGGAGCC GAGTCGGCGC GTTGTCTCCG GTGGCTGACC GCCTCGGACG TCCCCAGAGC 
CCATGCGCAG CCCCGGAGCG GGAAACTGAG GCGCTGAGGG CTGGCGTGGT GGTCGGGAGT 
CTGCCCGGCG TGTTTCTGGG TGGGGGAGGG GCCGGTCCTA TTATGCAGCG CATGTGGGCT 
CTGGCACCAT GGGTGCGCAT GTGCGCTGTC CGCGGGTTCC CGAGTGAGTT AGCTTTGCCA 
GCGGCTCCCT CCTCATCCCC TTTGCTTTCT GTGATCACAC GCAGAGACGC GGAAGATGCG 
GTGTACGGTC GCGACGGCTA CGATTACGAC GGCTACCGTC TGCGGGTAGA GTTTCCCCGA 
AGCGGCCGTG GGACCGGCCG AGGCGGCGGC GGGGGTGGAG GCGGCGGAGC CCCGAGAGGC 
CGCTATGGCC CGCCATCCAG GCGGTCTGAA AACAGAGTGG TTGTTTCTGG ACTGCCTCCG 
AGTGGAAGCT GGCAGGACTT AAAGGATCAC ATGCGTGAAG CAGGTGATGT ATGTTATGCT 
GATGTTTACC GAGATGGCAC TGGTGTCGTG GAGTTTGTAC GGAAAGAAGA TATGACGTAT 
GCAGTTCGAA AACTGGATAA CACTAAGTTT AGATCTCATG AGGGAGAAAC TGCCTACATC 
CGGGTTAAAG TTGATGGGCC CAGAAGTCCA AGTTATGGAA GATCTCGATC TCGAAGCCGT 
AGTCGTAGCA GAAGCCGTAG CAGAAGCAAC AGCAGGAGTC GCAGTTACTC CCCAAGGAGA 
AGCAGAGGAT CACCACGCTA TTCTCCCCGT CATAGCAGAT CTCGCTCTCG TACATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

SRSF1 promotes vascular smooth muscle cell proliferation through a ?133p53/EGR1/KLF5 pathway.
Nature communications816016(2017 Aug)
Xie N,Chen M,Dai R,Zhang Y,Zhao H,Song Z,Zhang L,Li Z,Feng Y,Gao H,Wang L,Zhang T,Xiao RP,Wu J,Cao CM


book

Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors.
Cancer research73(13)3974-86(2013 Jul)
Chettouh H,Fartoux L,Aoudjehane L,Wendum D,Clap?ron A,Chr?tien Y,Rey C,Scatton O,Soubrane O,Conti F,Praz F,Housset C,Rosmorduc O,Desbois-Mouthon C


book

Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society23(6)990-6(2013 Jul)
Iborra S,Hirschfeld M,Jaeger M,Zur Hausen A,Braicu I,Sehouli J,Gitsch G,Stickeler E


book

Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF.
Biochimica et biophysica acta1832(6)763-72(2013 Jun)
Piekielko-Witkowska A,Kedzierska H,Poplawski P,Wojcicka A,Rybicka B,Maksymowicz M,Grajkowska W,Matyja E,Mandat T,Bonicki W,Nauman P