Gene Symbol | CAV1 |
Entrez Gene ID | 404693 |
Full Name | caveolin 1 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
ORF » Species Summary » Sus scrofa » CAV1 cDNA ORF clone
gRNAs
Gene Symbol | CAV1 |
Entrez Gene ID | 404693 |
Full Name | caveolin 1 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
mRNA | Protein | Name |
---|---|---|
NM_214438.3 | NP_999603.2 | caveolin-1 isoform b |
NM_001348936.1 | NP_001335865.1 | caveolin-1 isoform b |
NM_001348935.1 | NP_001335864.1 | caveolin-1 isoform a |
NM_001348937.1 | NP_001335866.1 | caveolin-1 isoform b |
Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer.
Shen XJ, Zhang H, Tang GS, Wang XD, Zheng R, Wang Y, Zhu Y, Xue XC, Bi JW
International journal of biological sciences11(4)370-9(2015)
Transcription factor Sp1 is essential for the regulation of the porcine caveolin-1 gene.
Chen W, Chen Y, Qin L, Li A, Zhao X, Wang X, Xiao S, Mo D
DNA and cell biology30(7)491-7(2011 Jul)
Molecular characterization of caveolin-1 in pigs infected with Haemophilus parasuis.
Liu XD, Chen HB, Tong Q, Li XY, Zhu MJ, Wu ZF, Zhou R, Zhao SH
Journal of immunology (Baltimore, Md. : 1950)186(5)3031-46(2011 Mar)
Mutual effects of caveolin and nerve growth factor signaling in pig oligodendrocytes.
Schmitz M, Kl?ppner S, Klopfleisch S, M?bius W, Schwartz P, Zerr I, Althaus HH
Journal of neuroscience research88(3)572-88(2010 Feb)
Regulation of intracellular cholesterol distribution by Na/K-ATPase.
Chen Y, Cai T, Wang H, Li Z, Loreaux E, Lingrel JB, Xie Z
The Journal of biological chemistry284(22)14881-90(2009 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer
Title: Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer.
transcription factor Sp1 interacts with nucleotides -123/-114, indicating that Sp1 could play a key role in the transcriptional regulation of pig CAV-1
Title: Transcription factor Sp1 is essential for the regulation of the porcine caveolin-1 gene.
Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.
Title: Molecular characterization of caveolin-1 in pigs infected with Haemophilus parasuis.
The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF/TrkA signaling.
Title: Mutual effects of caveolin and nerve growth factor signaling in pig oligodendrocytes.
The plasma membrane Na/K-ATPase-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein pathway.
Title: Regulation of intracellular cholesterol distribution by Na/K-ATPase.
The following CAV1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAV1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe130684 | |
Clone ID Related Accession (Same CDS sequence) | NM_214438.3 , NM_001348936.1 , NM_001348937.1 | |
Accession Version | NM_214438.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-14 | |
Organism | Sus scrofa(pig) | |
Product | caveolin-1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU855654.4. On Feb 22, 2017 this sequence version replaced NM_214438.2. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EW666487.2, AY609931.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1487433, SAMN02584787 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_999603.2 |
CDS | 318..761 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe130684 | |
Clone ID Related Accession (Same CDS sequence) | NM_214438.3 , NM_001348936.1 , NM_001348937.1 | |
Accession Version | NM_001348936.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-14 | |
Organism | Sus scrofa(pig) | |
Product | caveolin-1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU855654.4. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ944830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584789, SAMN03031515 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001335865.1 |
CDS | 129..572 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe130684 | |
Clone ID Related Accession (Same CDS sequence) | NM_214438.3 , NM_001348936.1 , NM_001348937.1 | |
Accession Version | NM_001348937.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-14 | |
Organism | Sus scrofa(pig) | |
Product | caveolin-1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU855654.4. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK234499.1, BW966111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03031515, SAMN03031543 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001335866.1 |
CDS | 115..558 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGAGG AAATGAACGA GAAGCAAGTG TATGACGCGC ACACCAAGGA GATAGACTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe130685 | |
Clone ID Related Accession (Same CDS sequence) | NM_001348935.1 | |
Accession Version | NM_001348935.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-14 | |
Organism | Sus scrofa(pig) | |
Product | caveolin-1 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU855654.4. Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK394649.1, FS700749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787, SAMN02584789 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCGGGGG GCAAATACGT AGACTCAGAG GGACATCTCT ACACCGTCCC CATCCGGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001335864.1 |
CDS | 61..597 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCGGGGG GCAAATACGT AGACTCAGAG GGACATCTCT ACACCGTCCC CATCCGGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer. |
Transcription factor Sp1 is essential for the regulation of the porcine caveolin-1 gene. |
Molecular characterization of caveolin-1 in pigs infected with Haemophilus parasuis. |
Mutual effects of caveolin and nerve growth factor signaling in pig oligodendrocytes. |
Regulation of intracellular cholesterol distribution by Na/K-ATPase. |