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npc1 cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Summary

Gene Symbol npc1
Entrez Gene ID 100494646
Full Name NPC intracellular cholesterol transporter 1
Synonyms npca1
General protein information
Preferred Names

NPC intracellular cholesterol transporter 1

Names

Niemann-Pick C1 protein
Niemann-Pick disease, type C1
Gene Type protein-coding
Organism Xenopus tropicalis(tropical clawed frog)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_004915212.3 XP_004915269.1 Niemann-Pick C1 protein

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) NPC1 NP_001003107.1
Bos taurus (cattle) NPC1 NP_777183.1
Kluyveromyces lactis KLLA0F27137g XP_456287.1
Magnaporthe oryzae (rice blast fungus) MGG_00819 XP_003718164.1
Mus musculus (house mouse) Npc1 NP_032746.2
Drosophila melanogaster (fruit fly) Npc1a NP_001188769.1
Homo sapiens (human) NPC1 NP_000262.2
Pan troglodytes (chimpanzee) NPC1 XP_001155285.1
NPC1 XP_002800934.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP008137 XP_317322.4
Rattus norvegicus (Norway rat) Npc1 NP_705888.2
Danio rerio (zebrafish) npc1 NP_001230804.1
Saccharomyces cerevisiae (baker's yeast) NCR1 NP_015319.1
Eremothecium gossypii AGOS_AGL008W NP_986658.1
Neurospora crassa NCU04090 XP_956086.1
Arabidopsis thaliana (thale cress) AT1G42470 NP_174975.2
Gallus gallus (chicken) NPC1 XP_419162.3
Arabidopsis thaliana (thale cress) AT4G38350 NP_001190953.1
Xenopus tropicalis (tropical clawed frog) npc1 XP_004915269.1

Gene Ontology

The following npc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the npc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OXa11603 XM_004915212.3
Latest version!		 Xenopus tropicalis Niemann-Pick disease, type C1 (npc1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $713.30
$1019.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OXa11603
Clone ID Related Accession (Same CDS sequence) XM_004915212.3
Accession Version XM_004915212.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 3852bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-09-07
Organism Xenopus tropicalis(tropical clawed frog)
Product Niemann-Pick C1 protein
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030682.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2016 this sequence version replaced XM_004915212.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Xenopus tropicalis Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGTTCACCT GGAAGCACCA GTCCCTGATA CCGCTCTTCT TCCTAATAAC CCTGTGGCTT 
CCTGGGCGGG TATCTTCCCA GCACTGTGTC TGGTATGGGG AGTGTGGCAA TTCAACATTA 
GAAGACAAAC GGTTAAACTG TCGATACTCG GGGCCTCCTA TCTCCTTGCC TGAGGAAGGA 
CATACACTGC TACAGCAACT TTGCCCATCA CTTTATTATG GAAATAACAC AGTTTGCTGT 
GATGTCCAGC AACTCAACAC ACTTAACAGC AATCTTCAGC TTCCATTGCA GTTTCTTTCA 
AGATGCCCTT CTTGTTTTTA TAATTTCATG ACCATGTTCT GTGAGCTGAC CTGCAGTCCC 
TATCAGTCAG AGTTTCTAAA TGTTACCCAG ACTGAACCAT TTGTTGGGCC TAGTCCTCAA 
AGGGCAAATG AAAGCATTGT GGCCATGGAG TATTACATAG GAGAACAATT TGCTAATGCG 
ATGTACAATG CATGCAAGGA TGTAGAAGCC CCCTCGAGTA ATGTCAAGGC TTTGGCTTTG 
CTGTGTGGAA AGGATGTCAA GGACTGTAAT GCTACTAACT GGATTCAGTA CATGTTCAGC 
AAAGATAATG GGCAGGTTCC TTTTACCATC ACACCTATCT TTTCAGATGA TCCTGTGACT 
TCCATGCTTC CCATGAACAA CGCCACCAAG GGCTGCGATG AGCCTGTGGA AGAAGGCGGG 
GCTTCCTGTA GTTGTCAGGA CTGCGCTCTT TCTTGTGGTC CTGTGCCCCA GCCTCCACCA 
CTTCCTCCTC CATGGCTTAT ATTTGGCTTG GATGCTATGG CTGTCATCAT GTGGATAGTT 
TATGTTGTGT TCTTACTACT CTTTTCTGCA GTCATTATTG GATCGTGGTG TTACAGGAAA 
AAGAATATTG TCTCAGAATA TGCTCCTATT GATAGCACTT TAGCATATTC TGTCAATTCC 
ACTCCAATAG CAGGAGAGCC TTCGTGCTGT GACCGGCTTG GTGAAAGACT CGAGAACTTT 
CTTCGAATTG GATTTACAAA GTGGGGTTCA TTTTGCGTCC GGAAACCATG GATTGTTATC 
TTTTTCTCTG TGCTTTTAAT TGTGATATGT TGCTTTGGCC TCAAATACAT GAGGATTACT 
ACTGATCCTG TTGAACTCTG GTCAGATCCT CACAGCCAGG CTCGGCAAGA AAAGGAATAT 
TTTGACTCTC ACTTTGGACC CTTCTTTCGC ACTGAACAAC TAATCATCAC TGCCCCCAAC 
AGTTCAGTCC ACAATTACTC ACCATATCCT TCTGGCAGTG ATGTGCCTTT TGGCCCACCT 
CTAGACTTTA ATATTCTTGC TCAAGTCTTG GAGTTACAAA ATGGCATTGA AAACCTAAAA 
GCTTATTACA ATAATGAGAC TGTAATGTTA AAAGACATCT GTTTGGCTCC ATTGGCCCCA 
TACAACAACA ACTGCACAAT TTTCAGCGTT CTCAACTATT TCCAGAACAG CTTCTCTGTG 
CTGAATCATT CCATACAGGA TGATTTCTAT GTTTATGCTG ATTACCACAC TCACTTCTTA 
TACTGTGTGC GATCTCCAGC ATCTTTGAAT GACACATCAG TACTCCATGA TCCCTGCCTG 
GGAACATTTG GTGGCCCCAT ATTTCCATGG CTGGTTCTTG GAGGATATGA TGATGAAAAT 
TATAATAATG CCACCGCCCT GGTGATTACT TTTCCAGTAA ATAATTTCCG CAACGACACA 
GAAAAATTGA ATAGAGCAAA GGCTTGGGAA TTAGAGTTTA TCAAATTTGT GGAAAATTAT 
AGCAATCCCA ATCTGTCCAT TTCATTCTCT GCCGAGAGAA GCATTGAAGA TGAGATAAAC 
CGTGAAAGTA AAAGTGATGT TACTACTGTT GTCATCAGTT ATGCCTTAAT GTTTGTCTAC 
ATATCCTTGG CTTTGGGTCA GATTGGCCAC TGCAGTAGTA TCTTGGTGGA CTCTAAGATC 
TCGCTGGGTA TTGCTGGTAT TCTGATTGTG CTCAGTTCAG TAGCCTGCTC TCTGGGTATC 
TTCAGCTATG CTGGCGTGTC ACTCACTCTT ATTGTCATTG AGGTGATCCC ATTTCTGGTG 
CTAGCTGTTG GAGTTGACAA CATATACATT ATTGTGCAGA GATATCAGAG AGATGAGCGT 
CTTCATGATG AGACTCTGGA CCAGCAGATT GGCAGAATAC TGGGAGATGT GGCGCCGAGT 
ATATTTCTGT CAGCTTTTGC CGAAACGGTT GCCTTTTTTT TGGGAGCATT GTCCTCTATG 
CCAGCCGTGC GGACATTTTC ACTCTTTGCT GGGATGGCCG TGTTTCTAGA CTTCCTCCTT 
CAGATCACCT GCTTCATCAG CCTTCTTAGT CTGGACATCA GGCGACAAGA GAAAAACCGC 
TTAGATATCC TTTGCTGTGT GCCTGGATGC AAGAGAAACC GTGGCACTGA CAAACCGAAG 
AGCTGGCTGT TTTTGTTCTT CAAAAAGCTT TATGCCCCTG TACTGATGAA GGATTGGATA 
AGACCTATTG TGGTATCCGT TTTTGTTGGA ATCCTGTCCT TTAGCATTGC GGTTGTCAAC 
AAAGTAGAAA TAGGTCTTGA TCAGTCTCTC TCCATGCCTG ATGATTCCTA CATGCTAGAT 
TATTTTGGCT CACTCAGCAC ATACCTCCAT ACTGGCCCCC CAGTGTATTT TGTAGTTGAG 
GAAGGACATA ATTATACCAC AAAGGAAGGA CAGGACAAGG TGTGTGGTGG AGCTGGATGC 
AATAACAATT CATTGGTGCA AGAGATCTAC ACCGCTGCTG GGATAAGCAA CTATACAAGG 
ATCGGATACG CACCTTCCTC TTGGATTGAC GATTACTTTG ATTGGGTGAA GCCCCAGTCT 
ACTTGCTGTC GAATATATAA TAACACAGAT CAATTCTGTA ATGCTTCAGT GGTTAACGCA 
TCCTGCTTAT CATGCCGGTC CTACACTCCA GAAGGAAAGC GCAAACCAGT TGGAGAGGAT 
TTTATGCATT TCCTGCCCAT GTTTCTCTCT GATAATCCAA ACCCCAAATG TGGGAAAGGG 
GGCCACGCGG CATATGGCTC TGCAGTTGAT CTCCTTGACA GTAACACTAA TGTTGGTGCA 
ACTTATTTTA TGACCTATCA TACAATTCTG AAGAACTCCA CAGACTTCAT TGACGCCATG 
AGGAAAGCCC GTACCATCGC ACAGAATATC ACTGATAATA TGGACATCCC AGGGAAGAAA 
TACAAAGTAT TCCCTTACAG TATTTTCTAT GTATTTTATG AGCAGTATTT AACCATTGTG 
GATGACACCA TCTTCAACTT GTGCGTGTCT CTGGCAGCAG TATTCTTTGT GACAGTGATC 
CTTCTGGGCT TTGAGCTCTG GTCAGCTGTC CTTATGTGCA TCACGATTTC TATGATCCTT 
GTTAACATGT TTGGAGTCAT GTGGCTCTGG GGCATCAGCT TAAATGCAGT GTCCCTTGTC 
AATTTAGTCA TGAGCTGTGG CATTTCAGTA GAGTTCTGCA GCCACGTGAC CAGAGCCTTT 
TCAGTTAGCA CAAGGGGAAA CCGGGTACAA CGTGCTGAGG ATGCCCTGGC TCATATGGGT 
AGCTCGGTGT TCAGTGGTAT AACACTCACA AAGTTTGTTG GTATCGGTGT TCTTGGCTTG 
TCCAAATCTC AGATATTCAA GATCTTCTAC TTCAGAATGT ATCTGGCTAT GGTGCTTCTT 
GGGGCAGCAC ATGGCTTAAT ATTTCTGCCT GTTCTACTTA GTTACTTAGG CCCCCAAGTG 
AATAAAGCAA AGGTGCAAGC TGCGCTGCAG AGAGCCCGAG GCACAGAGCA AGAGCGTCTT 
TTTAACCACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_004915269.1
CDS408..4259
Translation

Target ORF information:

RefSeq Version XM_004915212.3
Organism Xenopus tropicalis(tropical clawed frog)
Definition Xenopus tropicalis Niemann-Pick disease, type C1 (npc1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_004915212.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGTTCACCT GGAAGCACCA GTCCCTGATA CCGCTCTTCT TCCTAATAAC CCTGTGGCTT 
CCTGGGCGGG TATCTTCCCA GCACTGTGTC TGGTATGGGG AGTGTGGCAA TTCAACATTA 
GAAGACAAAC GGTTAAACTG TCGATACTCG GGGCCTCCTA TCTCCTTGCC TGAGGAAGGA 
CATACACTGC TACAGCAACT TTGCCCATCA CTTTATTATG GAAATAACAC AGTTTGCTGT 
GATGTCCAGC AACTCAACAC ACTTAACAGC AATCTTCAGC TTCCATTGCA GTTTCTTTCA 
AGATGCCCTT CTTGTTTTTA TAATTTCATG ACCATGTTCT GTGAGCTGAC CTGCAGTCCC 
TATCAGTCAG AGTTTCTAAA TGTTACCCAG ACTGAACCAT TTGTTGGGCC TAGTCCTCAA 
AGGGCAAATG AAAGCATTGT GGCCATGGAG TATTACATAG GAGAACAATT TGCTAATGCG 
ATGTACAATG CATGCAAGGA TGTAGAAGCC CCCTCGAGTA ATGTCAAGGC TTTGGCTTTG 
CTGTGTGGAA AGGATGTCAA GGACTGTAAT GCTACTAACT GGATTCAGTA CATGTTCAGC 
AAAGATAATG GGCAGGTTCC TTTTACCATC ACACCTATCT TTTCAGATGA TCCTGTGACT 
TCCATGCTTC CCATGAACAA CGCCACCAAG GGCTGCGATG AGCCTGTGGA AGAAGGCGGG 
GCTTCCTGTA GTTGTCAGGA CTGCGCTCTT TCTTGTGGTC CTGTGCCCCA GCCTCCACCA 
CTTCCTCCTC CATGGCTTAT ATTTGGCTTG GATGCTATGG CTGTCATCAT GTGGATAGTT 
TATGTTGTGT TCTTACTACT CTTTTCTGCA GTCATTATTG GATCGTGGTG TTACAGGAAA 
AAGAATATTG TCTCAGAATA TGCTCCTATT GATAGCACTT TAGCATATTC TGTCAATTCC 
ACTCCAATAG CAGGAGAGCC TTCGTGCTGT GACCGGCTTG GTGAAAGACT CGAGAACTTT 
CTTCGAATTG GATTTACAAA GTGGGGTTCA TTTTGCGTCC GGAAACCATG GATTGTTATC 
TTTTTCTCTG TGCTTTTAAT TGTGATATGT TGCTTTGGCC TCAAATACAT GAGGATTACT 
ACTGATCCTG TTGAACTCTG GTCAGATCCT CACAGCCAGG CTCGGCAAGA AAAGGAATAT 
TTTGACTCTC ACTTTGGACC CTTCTTTCGC ACTGAACAAC TAATCATCAC TGCCCCCAAC 
AGTTCAGTCC ACAATTACTC ACCATATCCT TCTGGCAGTG ATGTGCCTTT TGGCCCACCT 
CTAGACTTTA ATATTCTTGC TCAAGTCTTG GAGTTACAAA ATGGCATTGA AAACCTAAAA 
GCTTATTACA ATAATGAGAC TGTAATGTTA AAAGACATCT GTTTGGCTCC ATTGGCCCCA 
TACAACAACA ACTGCACAAT TTTCAGCGTT CTCAACTATT TCCAGAACAG CTTCTCTGTG 
CTGAATCATT CCATACAGGA TGATTTCTAT GTTTATGCTG ATTACCACAC TCACTTCTTA 
TACTGTGTGC GATCTCCAGC ATCTTTGAAT GACACATCAG TACTCCATGA TCCCTGCCTG 
GGAACATTTG GTGGCCCCAT ATTTCCATGG CTGGTTCTTG GAGGATATGA TGATGAAAAT 
TATAATAATG CCACCGCCCT GGTGATTACT TTTCCAGTAA ATAATTTCCG CAACGACACA 
GAAAAATTGA ATAGAGCAAA GGCTTGGGAA TTAGAGTTTA TCAAATTTGT GGAAAATTAT 
AGCAATCCCA ATCTGTCCAT TTCATTCTCT GCCGAGAGAA GCATTGAAGA TGAGATAAAC 
CGTGAAAGTA AAAGTGATGT TACTACTGTT GTCATCAGTT ATGCCTTAAT GTTTGTCTAC 
ATATCCTTGG CTTTGGGTCA GATTGGCCAC TGCAGTAGTA TCTTGGTGGA CTCTAAGATC 
TCGCTGGGTA TTGCTGGTAT TCTGATTGTG CTCAGTTCAG TAGCCTGCTC TCTGGGTATC 
TTCAGCTATG CTGGCGTGTC ACTCACTCTT ATTGTCATTG AGGTGATCCC ATTTCTGGTG 
CTAGCTGTTG GAGTTGACAA CATATACATT ATTGTGCAGA GATATCAGAG AGATGAGCGT 
CTTCATGATG AGACTCTGGA CCAGCAGATT GGCAGAATAC TGGGAGATGT GGCGCCGAGT 
ATATTTCTGT CAGCTTTTGC CGAAACGGTT GCCTTTTTTT TGGGAGCATT GTCCTCTATG 
CCAGCCGTGC GGACATTTTC ACTCTTTGCT GGGATGGCCG TGTTTCTAGA CTTCCTCCTT 
CAGATCACCT GCTTCATCAG CCTTCTTAGT CTGGACATCA GGCGACAAGA GAAAAACCGC 
TTAGATATCC TTTGCTGTGT GCCTGGATGC AAGAGAAACC GTGGCACTGA CAAACCGAAG 
AGCTGGCTGT TTTTGTTCTT CAAAAAGCTT TATGCCCCTG TACTGATGAA GGATTGGATA 
AGACCTATTG TGGTATCCGT TTTTGTTGGA ATCCTGTCCT TTAGCATTGC GGTTGTCAAC 
AAAGTAGAAA TAGGTCTTGA TCAGTCTCTC TCCATGCCTG ATGATTCCTA CATGCTAGAT 
TATTTTGGCT CACTCAGCAC ATACCTCCAT ACTGGCCCCC CAGTGTATTT TGTAGTTGAG 
GAAGGACATA ATTATACCAC AAAGGAAGGA CAGGACAAGG TGTGTGGTGG AGCTGGATGC 
AATAACAATT CATTGGTGCA AGAGATCTAC ACCGCTGCTG GGATAAGCAA CTATACAAGG 
ATCGGATACG CACCTTCCTC TTGGATTGAC GATTACTTTG ATTGGGTGAA GCCCCAGTCT 
ACTTGCTGTC GAATATATAA TAACACAGAT CAATTCTGTA ATGCTTCAGT GGTTAACGCA 
TCCTGCTTAT CATGCCGGTC CTACACTCCA GAAGGAAAGC GCAAACCAGT TGGAGAGGAT 
TTTATGCATT TCCTGCCCAT GTTTCTCTCT GATAATCCAA ACCCCAAATG TGGGAAAGGG 
GGCCACGCGG CATATGGCTC TGCAGTTGAT CTCCTTGACA GTAACACTAA TGTTGGTGCA 
ACTTATTTTA TGACCTATCA TACAATTCTG AAGAACTCCA CAGACTTCAT TGACGCCATG 
AGGAAAGCCC GTACCATCGC ACAGAATATC ACTGATAATA TGGACATCCC AGGGAAGAAA 
TACAAAGTAT TCCCTTACAG TATTTTCTAT GTATTTTATG AGCAGTATTT AACCATTGTG 
GATGACACCA TCTTCAACTT GTGCGTGTCT CTGGCAGCAG TATTCTTTGT GACAGTGATC 
CTTCTGGGCT TTGAGCTCTG GTCAGCTGTC CTTATGTGCA TCACGATTTC TATGATCCTT 
GTTAACATGT TTGGAGTCAT GTGGCTCTGG GGCATCAGCT TAAATGCAGT GTCCCTTGTC 
AATTTAGTCA TGAGCTGTGG CATTTCAGTA GAGTTCTGCA GCCACGTGAC CAGAGCCTTT 
TCAGTTAGCA CAAGGGGAAA CCGGGTACAA CGTGCTGAGG ATGCCCTGGC TCATATGGGT 
AGCTCGGTGT TCAGTGGTAT AACACTCACA AAGTTTGTTG GTATCGGTGT TCTTGGCTTG 
TCCAAATCTC AGATATTCAA GATCTTCTAC TTCAGAATGT ATCTGGCTAT GGTGCTTCTT 
GGGGCAGCAC ATGGCTTAAT ATTTCTGCCT GTTCTACTTA GTTACTTAGG CCCCCAAGTG 
AATAAAGCAA AGGTGCAAGC TGCGCTGCAG AGAGCCCGAG GCACAGAGCA AGAGCGTCTT 
TTTAACCACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed