Gene Synthesis & DNA Synthesis Services
As a pioneer and leader in gene synthesis technology with over 600,000 completed gene synthesis projects for scientists around the world, GenScript has the expertise to help you achieve your DNA synthesis needs. DNA synthesis enables powerful solutions for molecular cloning, creating fusion proteins, or achieving sufficiently high protein expression levels. Compared to traditional molecular cloning techniques, GenScript's gene synthesis service saves both time and money while offering unparalleled top to bottom customizability. Up to date, the success rate and the on-time delivery rate of gene synthesis has achieved 99.95% and 98.5%, respectively. Geared up with proprietary technologies, GenScript offers guaranteed delivery time to ensure that your project is on track.
Gene Synthesis Service Options
|Types||Gene Length||Price (No hidden charge promise) †||Starting Turnaround Time (Business Days) *
||Starting Turnaround Time with Plasmid Prep Service (Business Days)|
|Standard Gene SynthesisGuaranteed||≤ 8 kb||View your discounted price online in as short as 1 minute||8||10|
|Fast Gene SynthesisGuaranteed||≤ 5 kb||7||9|
|Rush Gene SynthesisGuaranteed||≤ 4 kb||4US Manufacture||6US Manufacture|
|Economy Gene Synthesis||≤ 8 kb||10||12|
|GenBrick™ Gene Synthesis||> 8 kb||23||25|
† Typically, there is no additional charge on complexity of gene(s) or custom vector onboarding. We promise the transparency of each charge.
* The turnaround times here are estimates for non-complex genes. Turnaround time may increase as gene length and complexity increase. Please contact us to learn about discounted pricing for high-volume orders, institutional contracts, long-term partnerships, or to discuss your specific requirements. Be sure to check our current promotions.
Downstream services, including cloning, mutagenesis, plasmid prep and protein expression evaluation, are available at additional cost.
Customers retain all rights to the sequence data and related intellectual property.
Advantages of Custom Gene Synthesis
in easy to complex genes
|Custom Gene Synthesis
Any DNA sequence, even complex, GC-rich, repeated, or long genes, with 100% sequence accuracy guaranteed.
|Express Gene Synthesis
Delivery in as few as 4 days -- the fastest turnaround time in the industry.
|Genes Made in USA
First response team and local facility allows fastest delivery; Data security meets information regulatory.
Up to 200kb long DNA fragments, the fundamental building blocks of synthetic biology.
|Economy Gene Synthesis
Customized genes starting at $0.19/bp with no minimum order size and no difficulty limit.
GenSmart Instant Quote
An online interface to ease quote and ordering process with intelligent algorithm.
Free Construct Design
A smart and free design tool to accelerate transformation of ideas into functional plasmids.
|Free Codon Optimization
One click to maximize the expression of a functional protein by employing advanced and validated algorithm.
New! GenScript gene synthesis with guaranteed turnaround time! Terms and Conditions
The following are estimates based on typical orders; complex sequences may take longer. For a more accurate estimate based upon your specific needs, please request a quote.
|Sequence Length||Standard Gene SynthesisCat No. SC1010(Business Days)||Fast Gene SynthesisCat No. SC1619(Business Days)||Rush Gene SynthesisCat No. SC1575(Business Days)|
|≤454bp (mini-charge)||8 - 10 days||7 days||4 days|
|455 - 800 bp||8 - 10 days||9 days||4 days|
|801 - 1,500 bp||8 - 10 days||9 days||5 - 7 days|
|1,501 - 3,000 bp||10 - 12 days||11 days||7 - 9 days|
|3,001 - 5,000 bp||15 - 20 days||15 days||13 days (Up to 4,000 bp)|
|5,001 - 6,000 bp||20 - 25 days|
|6,001 - 8,000 bp||23 - 30 days|
For genes >8 kb in length, please order GenBrick™ Building Blocks for Synthetic Biology
Click on vector name below to see vector map and complete vector sequence
GenScript Standard Vectors1
Express Cloning Vectors2
Over 150 popular vectors for mammalian, bacterial, yeast, or baculovirus/insect expression systems.
See Vector List.
VectorArk™ Storage & Cloning
Free, secure storage of your custom or commercial vectors; $49 cloning into any of your archived vectors. Learn More »
Any commercial or custom vector of your choice.
1: GenScript Standard Vectors: Synthetic genes will be delivered in your choice of Standard Vector at no additional cost. There is no need to mail us an aliquot of the vector.
2: Express Cloning: Subcloning into any of these vectors is $49 and 2 days extra turnaround time for sequences <10 kb. There is no need to mail us an aliquot of the vector.
3. Subcloning into any other vector not listed here starts at $149 and 5 days to turnaround time for sequences <3 kb. Please mail in an aliquot of the vector.
The standard delivery includes:
- 4 μg of lyophilized plasmid containing your gene insert (1 μg for low-copy plasmid) *
- Sequence chromatograms covering your gene (electronic)
- Construct map for the plasmid (electronic)
- Quality assurance certificate
Typically, the synthesis success rate is mainly determined by DNA structures including repetitive sequences and GC content, and the stability in host cells including the toxicity for specific host cells. To improve the synthesis success rate of your gene sequences, we have summarized the main factors that we take into account for sequence analysis.
The main factors are including:
- Global GC content less than 20% or higher than 80%
- Various GC content within a DNA sequence
- Repeats of ≥ 20 bp
- The number and the length of small repeats
- Palindromic sequence
With over 18 years' experience on nucleotide synthesis, GenScript has fully developed state-of-the-art platform to handle both easy and difficult gene sequences. For the coding sequence, we strongly recommend codon optimization to reduce the difficulty. If you have any questions on our Gene Synthesis Services, please contact your technical account manager for details.
Quote and Ordering Process
GenScript offers an intelligent online smart quote system able to price any project instantly with best time and cost effective strategy in as short as 1 minute.
Our experienced Ph.D.-level project managers ensure that you receive professional service tailored to your needs and on-time delivery of ISO 9001 certifiedwhat\'s this? products with 100% sequence accuracy guaranteed.