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High Throughput Antibody Production (HTP Gene to Antibody) Service

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High throughput (HTP) antibody production by GenScript provides the most cost effective option for small-scale recombinant antibodies (ug to mg level). From customer-supplied antibody sequences (Fab or IgG) to final deliverables (purified recombinant antibodies or supernatant, QC data and report), HTP antibody production projects only take 18 business days! There is no additional set-up fee, and the cost of gene synthesis is waived.

This popular service combines GenScript's expertise in high throughput gene synthesis with a proprietary transient antibody expression technology to produce high quality recombinant antibodies for both therapeutic antibody drug candidates and reagent antibodies.

Antibody sequences accepted: hybriodma sequencing, hits (Fab or scFv) from display library based antibody discovery, single B cell and/or repertoire analysis via next generation sequencing (NGS), and more.

HTP Gene to Antibody Production Features

• 

  Fastest Turnaround
  Time in the Industry

  Express delivery of your
  antibodies in just 18 business days!

• 

  Flexible Options for Testing Recombinant Antibodies

  Multiple formats (Fc.fusion fragments) for expression; Flexible optional QCs

• 

  Cost Effective Option
  for your Investment

  One-stop solution: From
  gene synthesis to purified
  recombinant antibody.

HTP Gene to Antibody Production

Workflow

Service Specs

High Throughput Antibody Production (HTP Gene to Antibody) Service Details

Starting Material	Expression	Amount	Timeline	Deliverables	Price
Antibody Sequence (Minimum 4 samples)	Mammalian	10mL of supernatant (SC1946)	10 Business Days	10 mL of Crude Supernatant QC Data	Starting under $350 per antibody (including gene synthesis)
		100µg (SC1796)	18 Business Days	1-step affinity purified antibody as specified QC data	Starting under $500 per antibody (including gene synthesis)
		1mg (SC1797)
		Customized (SC1947)

• Project can begin from HTP gene synthesis or customer-supplied DNA but Antibody sequences are required for project evaluation in both cases.
• Turnaround time does NOT include shipping details. Please add approximately 3-5 days to account for shipping onto the dates listed.
• Pricing applicable to human IgG1, human IgG4, and mouse IgG2 a/b; Kappa (ĸ)/lambda(Λ) light chains.
• QC Data for SC1946 includes Western blotting against the Fc tag of the antibody to determine expression.
• QC Data for SC1796 & SC1797 includes A280 for Antibody concentration and SDS-PAGE for purity assessment.
• Additional QC such as SEC-HPLC, HTP ELISA, Endotoxin Testing, LC-MS, and peptide mapping available upon request (pricing may vary).

Applications

HTP Gene to Antibody Service Applications

This popular HTP gene to antibody service is designed to help researchers scale quickly from promising leads to purified recombinant antibodies in a microscale format, to accelerate their preliminary drug screening process. Applications served include epitope binning, ligand competition binding studies, affinity measurements, primary and secondary screen assays, HTP biophysical characterization to assess developability, and more.

Promising leads from your HTP studies can be seamlessly integrated into the GenScript workflow for scale up transient recombinant antibody production or stable cell pool/cell line production, for milligram to gram-level expression, which can support all your in vitro and in vivo applications.

Case Studies

Lane 1: Reducing  Lane2: Non-reducing

Recombinant Antibody Production-Related Services

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• Still unsure? Use this service guide to determine which is the best match for your application.

Discover the benefits of recombinant antibodies »

For more information about any other protein services, please visit our recombinant protein services main page or contact us using the information listed below.

Quotations and Ordering

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