iGEM IISER Bhopal
iGEM FCB- UANL
iGEM UPCH
iGEM IISER Berhampur
iGEM RUM-UPRM
iGEM iBowu-China
We are a group of undergrads from diverse academic backgrounds ranging from biology, chemistry to economics. United by our love for Synbio and iGEM. This is our 3rd iGEM team. With bronze in the 1st year, silver in the 2nd, ya know where we\'re going. This year our project aims to create an inexpensive and non-invasive therapy for diabetes. Our solution is a simple probiotic pill that is going to help regulate insulin levels by transforming gut cells into pancreatic cells!
Interviews
Fluorosurfactants (PFOs) are standard components of firefighting foams but pose an environmental threat. Our goal is to produce an ecofriendly alternative. We propose the use of Ranaspumin-2, a protein present in the bubble nests of Leptodactylus fragilis, to substitute PFOs as a foaming agent in firefighting mixtures. Not only will our project aid the environment, but it can reduce production costs of foams, allowing underfunded fire departments to access these tools.
Interviews
Meet the young and creative members of the new iGem2020 multidisciplinary team! We are currently developing an antifreeze product focused on diminishing the effects of frost on crops. This project will have a great impact in the agriculture of the Peruvian Andes. We hope we can show this concept to the world in the upcoming Virtual Giant Jamboree this year. Meet Crioprot!
Interviews
The IISER Berhampur iGEM team for 2020 is a group of undergraduate students hailing from diverse disciplines. This year marks our maiden attempt in participating in this competition. We aim to formulate an intervention strategy for Dengue Virus by combining mathematical modelling, in silico analysis and chemical biology. The essence is to design an efficacious reporter system to implement our strategy as possible therapeutics that may spark further research to combat this dreaded disease.
Interviews
As the first iGEM team in Puerto Rico and Caribbean, we aspire to continue impacting the social, educational, and research sectors of Puerto Rico including high school students, teachers and undergraduate students within Synthetic Biology, its application, and opportunities throughout hands on workshops. In the Giant Jamboree 2019, we won Silver Medal and were nominated for Best Project in Open Track. This year we look forward on participating the Giant Jamboree with our environmental project.
Interviews
We are iBowu-China2020, a high-school team from China. Our project is about delivering magnetic protein crystals to lung cancer cells with the aid of EGFR-binding ligand peptides and conducting targeted hyperthermia by heating up the protein crystals with alternating magnetic field. We are in need of funds for running activities in the Human Practices area as well as purchasing materials essential for the experiments. Please remember us when you cast your vote. We are grateful for your support!
Interviews
HIF-independent synthetic lethality
Science Signaling: HIF-independent synthetic lethality, Hilary Nicholson, Ph.D., Dana-Farber Cancer Institute
Application of Synthetic Biology
ACS Synthetic Biology: Application of Synthetic Biology, Nathan Hillson, Ph.D., Joint BioEnergy Institute, DOE
iGEM Team Montpellier
The BrownStanfordPrincetn iGEM team
iGEM Toronto
Congratulations! GenScript iGEM proposal review committee is pleased to announce the five winning teams as follows:
Each sponsored team will be eligible to receive:
Nordic iGEM Conference
GenScript gladly sponsored Nordic iGEM Conference 2019 on May 17th - 19th, at the University of Copenhagen, Denmark.
The 3rd iGEM Nanjing Regional Meetup
GenScript gladly sponsored The 3rd iGEM Nanjing Regional Meetup on May 19th, at China Pharmaceutical University, Nanjing, China.
Lumeng Ye, Ph.D., Senior Science, Research & Development, GenScript, jointed and offered technical workshop.
The 6th Conference of China iGEMer Community (CCiC)
GenScript sponsored The 6th Conference of China iGEMer Community (CCiC) on August 19th – 23rd, at Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences in Shenzhen, Shenzhen, China.
In addition, GenScript provided reagent and technical support to "Clone It" project, which included the following:
| Awards and Medals | |
| iGEM Munich 2018 |
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| iGEM at Stony Brook University |
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| iGEM_UCL |
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| The University of Washington iGEM team |
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| Virginia iGEM 2018 |
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| 2015 iGEM Teams sponsored by GenScript |
Country | Project | Award |
|---|---|---|---|
Cornell University |
USA - NY | Team Cornell genetically engineered E. coli to produce entericidin B peptide, providing resistance to microbes that cause bacterial coldwater disease (BCWD). |
Best Environment Project, Undergrad
Best Applied Design, Undergrad Best Supporting Entrepreneurship, Undergrad |
Nagahama iGEM |
Japan | Team Nagahama synthesized geraniol synthase genes from to provide volatile bacteria that can preserve food without electricity. |
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University College London (UCL) |
UK | Team UCL introduced controllable neurotransmitter biosynthetic pathways into gut microbes to treat mental illness. |
Best Supporting Entrepreneurship, Overgrad Nominated for Best New Composite Part, Overgrad |
University of Helsinki and Aalto university |
Finland | Team Aalto-Helsinki engineered E.coli to create propane from cellulose. |
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University of West Bohemia (Pilsen) AND Carles University (Prague) |
Czech Republic | Team Czech Republic developed an IOD Band system, using antigen recognition and cellular communication to identify circulating tumor cells. |
Finalist, Undergrad First Runner Up, Undergrad Best Health and Medicine Project, Undergrad Best Software Tool, Undergrad Best Model, Undergrad Nominated for Best Applied Design, Undergrad Nominated for Best Wiki, Undergrad Nominated for Best Presentation, Undergrad |
Wisconsin Lutheran College |
USA - WI | Team WLC focused on expanding phage therapy by developing a new method to isolate bacteriophages that infect pathogenic bacteria. |
Nominated by Best Education and Public Engagement, Undergrad
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Colorado State University |
USA - CO | Team CSU engineered E.coli to produce terpenoids by breaking down frying oil. |
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Evry |
France | Team Evry engineered S.cerevisiae to create a yeast immunotherapy targeting melanoma tumor cells. |
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Birkbeck - University of London |
UK | Team Birkbeck produced a viral modular chassis from lambda phages to detect pathogenic bacteria. |
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London Biohackspace |
UK | Team London Biohackspace used synthetic biology to create yeast strains that could be used in DIY homebrew kits. |
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Rock Ridge High School |
USA - VA | Team Rock Ridge HS created a bacterium that mimics insect-specific symbiotic bacteria to treat Lyme Disease. |
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Tec_Guadalajara (Tecnológico de Monterrey Campus Guadalajara) |
Mexico |
Team Tec_Guadalajara expressed a 2-gene metabolic pathways in yeast to produce industrial levels of graphene. |
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Tufts |
USA - MA | Team Tufts used Clostridium difficile toxin B to deliver CRISPR/Cas9 into epithelial cells and target deleterious genes. |
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University of Minnesota |
USA - MN | Team UMN used viral 2A sequences to optimized synthesis of beta carotenoids in yeast. |
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University of Pennsylvania |
USA - PA | Team Penn developed a biological analog of an octocoupler, mimicking cell-cell communication with bioluminescence. |
| 2014 iGEM Teams Sponsored by GenScript | Country | Team Project | Team Awards |
|---|---|---|---|
Germany |
Team Aachen developed a novel biosensor system called Cellock Holmes that detects pathogenic bacteria on solid surfaces using a low-cost, rapid and portable technique. | Best Supporting Software, Overgrad Safety Commendation, Overgrad Best Measurement Project |
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USA |
Team UCSF & UCB used cellular communities to model collective behaviors emergent from individual autonomous rules. Building upon quorum sensing mechanisms in the bioluminescent bacteria V. fischeri, they constructed a community averaging circuit in yeast. | Best Presentation, undergrad |
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Netherlands |
Team TU-Eindhoven engineered a new way to make genetically-engineered bacteria more resilient for use in environmental or biomedical applications, by designing two Clickable Outer Membrane Proteins that can allow bacteria to be easily encapsulated by a protective, biocompatible PEG shell. | Best New Application Project, Undergrad |
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Switzerland |
Team Zurich developed "Mosaicoli" cells that contain genetic circuits combining quorum sensing molecules with logic gates in order to model how complex patterns found in nature can emerge from simple rules, and to create new tools for creating biological computers. | Best Model, Overgrad |
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USA |
Team Cornell designed a novel lead remediation / heavy metal filtration system including bacterial strains engineered to simultaneously express heavy metal transport proteins and metallothioneins. | ||
Netherlands |
Team Groningen developed a new bandage, called LactoAid, to prevent common burn wound infections without the use of antibiotics. Lactococcus lactis was genetically engineered to secrete three multimodal infection-preventing molecules upon detection of Staphylococcus aureus and Pseudomonas aeruginosa at the wound site. | ||
Norway |
Team NTNU-Trondheim BioBricks that allow the insertion of transgenes into the photosynthetic organism Synechocystis sp. PCC 6803. to lay the groundwork for environmental innovations. | ||
USA |
Team Tufts expressed a merRNA from Bdellovibrio bacteriovorus in E. coli to sequester cyclic di-GMP and inhibit biofilm formation. | ||
USA |
Team Georgia Tech addressed the problem of dissolved methane entering water sources during fracking. They engineered E. coli to produce soluble methane monooxygenase (sMMO) in order to conver methane into the less volatile methanol, which can then be treated by further remediation pathways or extracted for commercial use. | ||
UK |
Team York developed EcoCADMUS (E. Coli CAdmium DecontaMination Universal System), a new system to provide a safe and effective way to remove Cadmium and Sulfate from wastewater. | ||
France |
Team Bordeaux worked to engineer ELASTICOLI -- E. Coli that generate elastin polymers that have the durability and flexibilty of plastics without posing the environmental risks of non-biodegradable plastic waste. | ||
USA |
Team Penn characterized the magnetotactic bacterium in terms of its cadmium tolerance, magnetism, and applications for synthetic biology. | ||
Germany |
Team Tuebingen created a system for the enzymatic conversion of blood erythrocytes from blood types A, B and AB to the universal donor blood type O. | ||
USA |
Team WLU-Milwaukee worked to engineer a probiotic bacterium to secrete the cellulase enzyme that will break down indigestible cellulose in plant material to its digestible glucose components, so that plant material that would ordinarily be indigestible waste can instead be converted into digestible sugar. | ||
USA |
Team CSU Fort Collins worked to build a pathway that breaks down spent frying oil in order to manufacture a value-added terpenoid. | ||
UK |
Team Manchester created a novel treatment for obesity by engineering E. coli into a "sugar sponge" that absorbs excess carbohydrates before they can be taken up in the human intestines. |
| 2013 iGEM Teams Sponsored by GenScript | Country | Team Project | Team Awards |
|---|---|---|---|
Albert Ludwigs University Freiburg |
Germany |
Team Freiburg developed the uniCAS universal toolkit that enables customizable gene regulation in mammalian cells utilizing the CRISPR/Cas9 system for specific targeting of DNA sequences, which can be matched with different effector domains for efficient gene activation or repression. |
Regional Gold Medal Advance to World Championship Regional Finalist, Europe Best New BioBrick Part or Device, Engineered World Championship Best Foundational Advance Project |
Instituto Tecnológico y de Estudios Superiores de Monterrey |
Mexico |
Team TecMonterrey engineered bacterial cells to fight cancer, by targeting anaerobic bacteria to the hypoxic tumor microenvironment where they can secrete therapeutic proteins that induce apoptosis selectively in tumor cells. |
Regional Gold Medal Advance to World Championship Best Presentation Best Human Practices Best New BioBrick Part or Device, Engineered |
Shanghai Jiao Tong University |
China |
Team SJTU-Bio-X created a Metabolic Gear Box combining light sensors with CRISPR interference technology to allow in vivo metabolic flux regulation. As a proof-of-principle, they demonstrated light-inducible repression of fatty acid synthesis. |
Regional Gold Medal Advance to World Championship |
Nanjing University |
China |
Team Nanjing-China designed the Atrazine Elf, a bacteria that can sense, uptake,and degrade the ubiquitous herbicide atrazine from soil and water. |
Regional Gold Medal Advance to World Championship |
Hokkaido University |
Japan |
Team Hokkaido created a Random Operon Shuffling Kit to mix and match transcriptional promoters and ribosomal binding sites in order to optimize gene expression. |
Regional Silver Medal Advance to World Championship |
Turgut Ozal University |
Turkey |
Team ATOMS-Turkiye sought to fight cancer by engineering gut e. coli to detect the EpCAM antigen present on cancer cell membranes and to express cancer-specific apoptotic proteins under the control of bacterial quorum-sensing mechanisms. |
Regional Gold Medal |
Bandung Institute Technology (ITB) |
Indonesia |
Team ITB_Indonesia designed a bacterial cell biosensor for aflatoxins (ubiquitous mutagens and carcinogens produced by fungal growth on improperly stored nuts and other staple foods) in order to improve food safety. |
Regional Silver Medal |
UNAM School of Science |
Mexico |
Team Ciencias-UNAM engineered gut-dwelling E. coli to fight gastritis by secreting antimicrobial peptides under the control of quorum-sensing mechanisms upon detection of gastritis-causing H. pylori. |
Regional Silver Medal |
LIMES Institute at the University of Bonn |
Germany |
Team Bonn generated a photoswitachble protein degradation system employing a light-sensing domain from Avena sativa to allow blue-light-inducible degradation of any protein of interest. |
Regional Bronze Medal |
Instituto Tecnologico de Costa Rica |
Costa Rica |
Team Costa_Rica_Cibus engineered bacterial cells to transform whey into biodiesel by expressing genes that increase the ability to metabolize lactose into triacylglycerols. |
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Rutgers University |
USA |
Team Rutgers aimed to limit the growth of antibiotic-resistant bacteria by developing a self-regulatory system for degrading virulent factors using quorum-sensing mechanisms in pathogens such as pseudomonas aeruginosa. |
| 2012 iGEM Teams Sponsored by GenScript | Country |
|---|---|
| Autonomous University of Nuevo León | Mexico |
| Albert Ludwigs University Freiburg | German |
| Boston University | USA |
| Caltech | USA |
| ITESM University | Mexico |
| Johns Hopkins University | USA |
| MIT | USA |
| PeKing University | China |
| Shanghai Jiao Tong University | China |
| University of St. Andrews | England |
| University of Tokyo | Japan |
| 2011 iGEM Teams Sponsored by GenScript | Projects | Latest Developments |
|---|---|---|
| Uppsala-Sweden | Setting the color Improving the existing multichromatic sensing systems by expanding the number of useful wavelengths. |
Advance to World Championship |
| NYMU-Taipei | Tailoring Your Avatar Create wireless neuro-stimulator, focusing on achieving remote neuro-stimulation to minimize the invasion and damage to the neuron. |
Advance to World Championship |
| SJTU-BioX-Shanghai | Condon Switch Controlling Protein Biosynthesis Designing a set of Codon-Switches that regulate target protein biosynthesis (translation). |
Advance to World Championship |
| St Andrews | Kill Switch Engage Bricking an antimicrobial peptide-encoding gene under the control of an inducible promoter, a kill switch was designed for E. coli suicide upon induction. |
Regional Gold medal |
| UCL London | Supercoiliology |
Regional Bronze medal |
| UIUC-Illinois | E. chiver Dynamically Efficient Bacteria: Creating a "Bacterial Filing Cabinet". |
Regional Bronze medal |
| Utah State | Cyano Bricks Producing high value bioproducts from Synechocystis sp PCC 6803, and studying properties of 23 promoters using dual luciferase imaging technology. |
Regional Gold medal |
| Valencia | Water Colicin Cleaner: disinfected water by E. coli Disinfecting water pathogens by bacteriocin, which can be secreted by engineered E. coli under well controlled manners, e.g. through pH Stat<. |
| 2010 iGEM Teams Sponsored by GenSript | Result |
|---|---|
| SJTU-BioX-Shanghai | Gold medal |
| Uppsala-Sweden | Bronze medal |
| Utah_State | Gold medal |
| 2009 iGEM Teams Sponsored by GenSript | Result |
|---|---|
Silver medal |
