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The clinical study of immune checkpoint proteins achieved great success, making immunotherapy a promising method to treat cancer. Immune checkpoints are involved in a series of immunomodulatory pathways that can either co-stimulate or co-inhibit the immune response. Co-stimulatory immune checkpoints enhance the body's immune response against pathogens. Co-inhibitory immune-checkpoints can negatively regulate T cell's activity to protect against pro-inflammatory reactions. Targets, such as PD-1, PD-L1, B7, CD28, TIM and CD226, are very hot in cancer treatment.
GenScript immune checkpoint recombinant proteins passed a variety of activity testing and are featured with high purity and batch to batch stability. They are used as immunogens for the production of GenScript immune checkpoint antibodies.
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