Overview

Immune checkpoints provide broad and diverse opportunities to enhance T cell activity that can increase anti-tumor immunity, potentially resulting in durable clinical responses. GenScript has developed overexpression cell line products expressing the most popular co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and clinical translation.

Highlights

Single clone

Single Clone

Multiple Species

Multiple Species

Guaranteed performance

Guaranteed Performance

Stringent QC standards

Stringent QC Standards

Applications

Screening antibodies binding with immune checkpoints

Evaluating binding affinity between antibodies with immune checkpoints

Using as immunogen for antibody development

Receptor List

Co-Stimulatory Immune Checkpoints
4-1BB OX40 GITR ICOS B7-H2
B7-H3 B7-H4 HVEM

Product List

Receptor Cell Line Cat.No.
PD-1 CHO-K1/PD-1
CHO-K1/mouse PD-1
CHO-K1/cyno PD-1
Daudi/PD-1 M00630
PD-L1 HEK293/PD-L1 M00544
CHO-K1/PD-L1
CHO-K1/mouse PD-L1
CHO-K1/cyno PD-L1 New M00573
PD-L2 CHO-K1/PD-L2
CHO-K1/cyno PD-L2 M00629
CTLA4 CHO-K1/CTLA4
CHO-K1/mouse CTLA4
CHO-K1/cyno CTLA4
Lag3 CHO-K1/Lag3 New M00532
TIGIT CHO-K1/TIGIT
CHO-K1/mouse TIGIT New M00585
Tim3 CHO-K1/Tim3
VISTA CHO-K1/VISTA New M00533
CHO-K1/Mouse VISTA M00633
CHO-K1/Cyno VISTA M00634
BDCA2 CHO-K1/BDCA2
CHO-K1/Cyno BDCA2
CHO-K1/BDCA2 and FcER1G
CHO-K1/ Cyno BDCA2 and FcER1G
BTLA CHO-K1/BTLA
KIR CHO-K1/KIR M00650
CD38 CHO-K1/human CD38 M00553
CHO-K1/mouse CD38 M00636
CD47 CHO-K1/CD47
CHO-K1/Mouse CD47 M00631
CHO-K1/Cyno CD47 M00632
CD80 CHO-K1/CD80 M00545
CD103 CHO-K1/ITGAE
CD112 CHO-K1/CD112
CD155 CHO-K1/CD155
CHO-K1/Cyno CD155
CHO-K1/Mouse CD155
CD200 R1 CHO-K1/CD200 R1
Receptor Cell Line Cat.No.
4-1BB CHO-K1/4-1BB New M00538
CHO-K1/mouse 4-1BB
CHO-K1/cyno 4-1BB
OX-40 CHO-K1/OX-40
GITR CHO-K1/GITR
ICOS CHO-K1/ICOS M00649
B7-H2 CHO-K1/B7-H2
B7-H3 CHO-K1/B7-H3
B7-H4 CHO-K1/B7-H4
HVEM CHO-K1/HVEM M00646
CHO-K1/mouse HVEM M00647
CHO-K1/Cyno HVEM M00648

Resources

Stable Cell Lines Brochure
Stable Cell Lines Brochure

Cell line product catalog including brief introductions, product list and validations.

Free Download
Fc Receptor Cell Lines Flyer
Fc Receptor Cell Lines Flyer

Cell line product catalog including brief introductions, product list and validations.

Free Download

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