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Catalog Products » Other Products » Endotoxin Detection and Removal System » Endotoxin Removal » ToxinEraserTM Endotoxin Removal Resin

ToxinEraser™ Endotoxin Removal Resin

Lipopolysaccharide (LPS) is a bacterial endotoxin and a major constituent of the cell walls of gram-negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, or fatal shock in mammalian hosts. The removal of these endotoxins is highly necessary for downstream processes.
The ToxinEraserTM Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide.

Total Volume
2 ml of 50% slurry

Key Features
Key Features
  • Superior Stability: This product has both high stability and high removal efficiency.
  • Excellent Binding Capacity: ToxinEraserTM has a binding capacity of over 2,000,000 EU/ml (CV).
  • Strong Resilience: This product may be reused up to five times if properly regenerated.

Storage Store at 2°C to 8°C. Do not freeze.

Cat. No. Product Name Quantity Price
ToxinEraser™ Endotoxin Removal Kit - 1 kit
ToxinSensor™ Gel Clot Endotoxin Assay Kit - 1 Kit
ToxinSensor™ Chromogenic LAL Endotoxin Assay Kit - 1 Kit (16 rxns)
ToxinSensor™ Endotoxin-free Pipette Tips (1 ml, Blue) - 1 PK of 6 tips
ToxinSensor™ Endotoxin-free Tubes - 10 Tubes
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Zhu L., et al. Construction, purification, and evaluation of multivalent DNA vaccine against Schistosoma japonicum. Parasitol Res. 2011 Jan;108(1):115-21.

Xia L., et al. PTD‐hFOXP3 protein acts as an immune regulator to convert human CD4 CD25− T cells to regulatory T‐like cells. J Cell Biochem. 2012 Dec;113(12):3797-809.

Sadraeian M., et al. Prevention and Inhibition of TC-1 Cell Growth in Tumor Bearing Mice by HPV16 E7 Protein in Fusion with Shiga Toxin B-Subunit from Shigella dysenteriae. Cell J. 2013 Jul;15(2):176-81.

Hao J., et al. rFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner.Cell Mol Immunol. 2013 Oct 7. doi: 10.1038/cmi.2013.44.

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Cat. No. L00402
Size Price
1 ml $60.00