Off-target effects remain a major concern in CRISPR-mediated immunotherapies. Read on and learn how a chemical toolbox can be developed in an effort to overcome this problem.
Sep 16, 2021
The development of numerous vaccines against SARS-CoV-2 worldwide within one year of the pandemic is unprecedented and undoubtedly a huge accomplishment in human history.
Aug 18, 2021
The study reveals the capacity of lymphangiogenic vaccines to promote a potent anti-cancer T cell immunity, and suggests a new protective and therapeutic approach to fight solid tumors.
Jul 22, 2021
Rana, Jyoti, et al. "CAR and TRuC redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII." Molecular Therapy (2021).
Jun 09, 2021
Liu, Yinghui, et al. "Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2." Proceedings of the National Academy of Sciences 118.12 (2021).
May 06, 2021
Molnar, Sebastian, et al. "Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5." MAbs. Vol. 12. No. 1. Taylor & Francis, 2020.
Mar 23, 2021
Hanna, Ruth E., et al. "Massively parallel assessment of human variants with base editor screens." Cell 184.4 (2021): 1064-1080.
Mar 23, 2021