- Research Digest
8 Results
More RNA Vaccines: More Hopes for Stopping the Pandemic
Various vaccines based on different types of RNA are now under development to fight emerging SARS-CoV-2 variants, bringing new hopes for stopping the long-standing pandemic.
09-28-2021Read More »
Regulating Cas Proteins: A Chemical Toolbox Aiding Genome Editing
Off-target effects remain a major concern in CRISPR-mediated immunotherapies. Read on and learn how a chemical toolbox can be developed in an effort to overcome this problem.
09-16-2021Read More »
Fight the Pandemic: Super Antibodies Coming to the Rescue
The development of numerous vaccines against SARS-CoV-2 worldwide within one year of the pandemic is unprecedented and undoubtedly a huge accomplishment in human history.
08-18-2021Read More »
Promoting Anti-cancer Immune Responses Using Lethally Irradiated Tumor Cells
The study reveals the capacity of lymphangiogenic vaccines to promote a potent anti-cancer T cell immunity, and suggests a new protective and therapeutic approach to fight solid tumors.
07-22-2021Read More »
Curbing Anti-drug Antibody Enthusiasm Through CAR- and TRuC-redirected Regulatory T Cells
Rana, Jyoti, et al. "CAR and TRuC redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII." Molecular Therapy (2021).
06-09-2021Read More »
Unraveling Potential Hosts of SARS-CoV-2 with ACE2 Orthologs
Liu, Yinghui, et al. "Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2." Proceedings of the National Academy of Sciences 118.12 (2021).
05-06-2021Read More »
Production of Novel Monoclonal Antibodies Against the SERINC5 HIV-1 Restriction Factor
Molnar, Sebastian, et al. "Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5." MAbs. Vol. 12. No. 1. Taylor & Francis, 2020.
03-23-2021Read More »
Base Editor Screens, a New Approach for Readily and Scalably Functionalizing Genetic Variants
Hanna, Ruth E., et al. "Massively parallel assessment of human variants with base editor screens." Cell 184.4 (2021): 1064-1080.
03-23-2021Read More »
