New Vaccine Targets Delta, Omicron, and Potential Variants

A recent study revealed the dynamic evolutionary pathway of the SARS-CoV-2 S protein for the first time and proposed a novel strategy for vaccine design that can be utilized to fight Delta, Omicron, and potential future variants.

Mar 09, 2023

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Broad-Spectrum Antibodies against All SARS-CoV-2 Variants

A group of researchers developed a screening strategy for neutralizing antibodies based on cold linear epitopes and successfully identified broadly cross-reactive and protective human neutralizing antibodies target

Mar 09, 2023

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Designing Helical Synthetic Peptides to Target Globular Proteins

Scientists at the Institute for Research in Biomedicine (IRB Barcelona) have implemented a new peptide design that leverages their learnings from the helical properties of polyglutamine (PolyQ) containing proteins.

Dec 27, 2022

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Improving CAR-T Therapy with CRISPR

An innovative type of non-viral, PD1-integrated CAR-T cells was developed and showed superior ability to safely fight tumor cells in patients with non-Hodgkin lymphoma in a phase I clinical trial.

Nov 28, 2022

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Improving Engineered T Cells by CRISPRing RASA2 Expression

Learn how the Alexander Marson lab at Gladstone-UCSF has identified a new intrinsic molecular checkpoint in T cells involved in modulating antigen sensitivity, cytotoxicity, and persistence.

Oct 25, 2022

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Individualized mRNA Neoantigen Vaccine Fights against Solid Tumors

An individualized mRNA-based vaccine induces strong, persistent, and functional tumor-specific T cell responses in patients with advanced metastatic solid tumors.

Sep 20, 2022

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Newly Developed Biosensor Combines HER2 Affibody and Marine Luciferase

Learn about a newly developed optical biosensor that takes advantage of the small size and specificity of affibodies and the high bioluminescent activity of a new luciferase from Metridia lucens copepod (MlLuc).

Aug 29, 2022

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Improved Adenine Base Editor Minimizes Undesired Edits for Gene Therapy

A newly developed next-generation adenine base editor may improve the safety of human gene therapy.

Aug 21, 2022

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