From gene synthesis to lentivirus packaging as fast as 4 weeks!
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Turnaround time starts from 4 weeks!
Seamless Delivery of Your Candidate Genes In Your Selected Lentivirus
Fast Delivery in 4 weeks
Superior Transduction Performance
One Stop Shop
Gene Length | Lentivirus Titer (TU/mL) | Lentivirus Volume | Application | Total TAT | |
---|---|---|---|---|---|
Gene-to-Lentivirus Package | ≤ 3000bp | 107 | 1 mL | Cell Culture | Start from 4 weeks * |
2 mL | |||||
108 | 1 mL | ||||
2 mL |
*Not applicable for genes with complex sequence or in vivo studies. Learn more about gene sequence difficulty rules>>
Typically, the synthesis success rate is mainly determined by DNA structures including repetitive sequences and GC content, and the stability in host cells including the toxicity for specific host cells. To improve the synthesis success rate of your gene sequences, we have summarized the main factors that we take into account for sequence analysis.
The main factors are including:
With over 18 years experience on nucleotide synthesis, GenScript has fully developed state-of-the-art platform to handle both easy and difficult gene sequences. For the coding sequence, we strongly recommend codon optimization to reduce the difficulty. If you have any questions on our Gene Synthesis Services, please contact your technical account manager for details.
Cell therapies using lentiviral vectors have demonstrated noteworthy clinical success in patients with B-cell malignancies leading to regulatory approval of the first genetically engineered cellular therapy. As the top one global provider of gene synthesis, GenScript offers an integrated package from gene synthesis to lentivirus packaging. Customers only need to provide their gene sequences, and GenScript takes care of the rest.
Lentivirus is predominantly used in cell model establishment because it can infect difficult-to-transfect cells, and improve the transduction efficiency. Also, its integrating capability ensures that the target genes can integrate into cellular genome and achieve stable expression.
Lentiviral vectors improve the screening methodology in terms of stability and efficiency relevance. Also, lentiviruses are an important model that can provide new insights into the mechanisms of viral entry and forms a basis for antiviral drug screening.
Lentiviral gene delivery system offers many potentially unique advantages, such as long-term and stable gene expression, and infecting non-dividing cells. GenScript can provide lentivirus-based gene overexpression and gene knockdown services for your gene functional studies.