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CHO-K1/D2/Gα15 Stable Cell Line

Synonyms Human Recombinant D2 Dopamine Receptor Stable Cell Line
Description Dopamine is the predominant catecholamine neurotransmitter found in mammalian brain, where it controls a variety of functions including locomotor activity, cognition, emotion, positive reinforcement, food intake, and endocrine regulation. It also plays multiple roles in the periphery as a modulator of cardiovascular function, catecholamine release, hormone secretion, vascular tone, renal function, and gastrointestinal motility. The dopamine receptor family consists of five members, which are classified into two groups, D1-like (D1 and D5) and D2-like (D2, D3, and D4). Dopamine receptor 2 is mainly expressed in the brain. It has splicing variants, D2L and D2S. D2R receptor is implicated in a number of neurological and psychiatric conditions. Drugs acting at dopamine D2 receptors (D2R) are commonly used to alleviate symptoms for Parkinson's disease, schizophrenia, and depression.
Species Human
Culture Medium Ham's F12, 10% FBS, 200 μg/ml Zeocin,100 μg/ml Hygromycin B
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

Functional assays for D2 receptor

  • CHO-K1/D2/Gα15 Stable Cell Line
  • CHO-K1/D2/Gα15 Stable Cell Line

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Cat. No. M00152
2 vials $8500.00