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293/MC3/CRE-Luc Stable Cell Line

*This product has been discontinued!*
Synonyms Human Recombinant MC3 Melanocortin Receptor Stable Cell Line
Description The melanocortin receptor 3 (MC3 receptor) is Gs-coupled GPCRs expressed in brain, placental, and gut tissues but not in melanoma cells or in the adrenal gland. MC3 receptor knockouts exhibit a metabolic syndrome. At 4-6 months old, MC3 receptor knockout mice show increased fat mass, reduced lean mass and a higher feed efficiency, with normal metabolic rates. MC3 knockout mice are hyperleptinaemic and males are often mildly hyperinsulinaemic. GenScript's cloned human MC3R-expressing cell line is made in the 293/CRE-Luciferase host.
Species Human
Culture Medium DMEM, 10% FBS, 50 μg/ml Hygromycin B, 100 μg/ml Zeocin
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

Functional assay for MC3 receptor

Cat. No.
Product Name
Melanotan (MT)-II - 5 mg
γ-1-Melanocyte Stimulating Hormone (MSH), amide - 1 mg
α-Melanocyte-Stimulating Hormone (MSH), amide - 5 mg
α-Melanocyte-Stimulating Hormone (MSH), amide - 1 mg

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