×
Catalog Products » Other Products » Stable Cell Lines » Human Recombinant Niacin Receptor 1 Stable Cell Line

CHO-K1/NIACR1/Gα15 Stable Cell Line


Synonyms Human Recombinant Niacin Receptor 1 Stable Cell Line
Description GPR109A is a high affinity receptor for nicotinic acid (niacin) and is a member of the nicotinic acid receptor family of G protein-coupled receptors (the other identified member being GPR109B). GPR109A is a Gi/o protein-coupled receptor with high affinity for nicotinic acid. In GPR109A knockout mice, the effects of niacin on both lipids and flushing are eliminated. Furthermore in arrestin beta 1 knockout mice, niacin's effect on flushing is greatly reduced while the lipid modifying effects are maintained. GPR109A is believed to be an important biomolecular target of niacin which is a widely prescribed drug for the treatment of dyslipidemia and to increase HDL cholesterol but whose therapeutic use is limited by flushing.
Species Human
Culture Medium Ham's F12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/NIACR1/Gα15 Stable Cell Line
CHO-K1/NIACR1/Gα15 Stable Cell Line




Notice there is no results found, you can visit "Citations Database" for other results.






For more documents, please visit "Technical Support".
Cat. No. M00428
Size
Price
2 vials $8500.00
24 hour
 
*
*
*
*