Catalog Products » Human Recombinant D4 Dopamine Receptor Stable Cell Line

293EC18/D4 Stable Cell Line

*This product has been discontinued!*
Dopamine is the predominant catecholamine neurotransmitter found in mammalian brain, where it controls a variety of functions including locomotor activity, cognition, emotion, positive reinforcement, food intake, and endocrine regulation. It also plays multiple roles in the periphery as a modulator of cardiovascular function, catecholamine release, hormone secretion, vascular tone, renal function, and gastrointestinal motility. The dopamine receptor family consists of five members, which are classified into two groups, D1-like (D1 and D5) and D2-like (D2, D3, and D4). The D4 receptor inhibits the enzyme adenylate cyclase, thereby reducing the intracellular concentration of the second messenger cyclic AMP. The D4 receptor is linked to many neurological and psychiatric conditions including schizophrenia, Parkinsons disease, bipolar disorder, addictive behaviors including sex addiction, and eating disorders such as anorexia nervosa, bulimia nervosa and binge eating.
M00477
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Synonyms

Human Recombinant D4 Dopamine Receptor Stable Cell Line

Overview
Applications Functional assays for D4 receptor

Product Introduction
Storage iquid nitrogen immediately upon delivery
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS,10% DMSO
Culture Medium Ham's F12, 10% FBS, 200 μg/ml Zeocin

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