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Catalog Products » Other Products » Mouse Recombinant PD-L1 Stable Cell Line

CHO-K1/mouse PD-L1 Stable Cell Line

*This product has been discontinued!*
Synonyms CD274 ; B7-H; B7H1; PDCD1L1; PDCD1LG1; PDL1
Description Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes. After that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis, which is further mediated by a downregulation of the Bcl-2 gene.
Species mouse
Culture Medium F12K, 10% FBS, 600 μg/ml G418
Freeze Medium 95% complete growth medium, 5% DMSO

Stability 15 passages
Storage Liquid nitrogen immediately upon receiving

Binding assays or use as immunogen




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