Catalog Products » Other Products » Human Recombinant CD16A 158F Stable Cell Line

CHO-K1/CD16A 158F Stable Cell Line

*This product has been discontinued!*
Synonyms FCGR3A, FCG3, FCGR3
Description CD16 is a cluster of differentiation molecule found on the surface of natural killer (NK) cells, monocytes and macrophages. It can be used to isolate populations of NK cells by antibodies directed towards CD16, using fluorescent-activated cell sorting or magnetic-activated cell sorting. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). The two isoforms of the CD16a stimulatory receptor found on NK cells and macrophages differ by one amino acid at codon 158 (V/F) and are important for antibody-dependent cell-mediated cytotoxicity (ADCC). The high affinity 158 V/V homodimer of CD16A is present on approximately 20% of the population and the lower affinity F/F homodimer and F/V heterodimer are present in the remaining 80%.
Species human
Culture Medium F-12K, 10% FBS, 100 μg/ml Hygromycin B, 4 μg/ml Puromycin
Freeze Medium 95% complete growth medium, 5% DMSO

Stability 15 passages
Storage Liquid nitrogen immediately upon receipt

Binding assay or use as immunogen

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