Monkeypox Virus

Monkeypox is a zoonotic disease meaning it is passed from animals to humans. It is caused by the monkeypox virus and is an enveloped double-stranded DNA virus that belongs to the Orthopoxvirus genus. The monkeypox virus includes two distinct clades, the central African (Congo basin) and the west African clade. Other similar orthopoxvirus diseases include smallpox and cowpox.

The monkeypox virus was first identified in humans in 1970, in Africa, and its transmission is most likely due to African rodents and non-human primates. In May 2022, it was detected in multiple countries outside of its endemic area of central and west Africa prompting the W.H.O. to declare an international health emergency. After reaching more than 6,600 cases, the United States followed with a public health emergency declaration on August 4, 2022.

The recommended detection method is PCR and the preferred sample type is swabbed lesion or lesion crusts. These are known to contain the most concentrated amount of virus. Secondary sample types like blood or saliva require further investigation since there may be detection limitations due to infection stage. Always refer to the CDC website for the most up-to-date information.

GenScript offers a variety of detection solutions that are important to the study of monkeypox disease spread and surveillance.

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Real-time PCR Test

The Monkeypox Virus Real-time PCR Test provides an easy and reliable kit for the detection of monkeypox virus. It targets the amplification of 2 conserved regions detected by designed primers with FAM- and HEX-labeled fluorescent probes. The kit additionally includes an internal control (human RNase P gene) labeled with CY5.

For Research Use Only.

Not for use in diagnostic procedures.

Please inquire for CE-mark IVD use.

cytosinct
  • 2 conserved gene targets (F3L and B6R)
  • Lyophilized reagents
  • Compatible with most thermocyclers and extraction kits

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Pseudovirus Validation Product A

The Monkeypox Virus F3L and B6R Validation Product A is purified pseudovirus containing each of the conserved monkeypox genes, F3L and B6R. This product is intended to be used as a positive standard and internal standard control.

For Research Use Only.

Not for use in diagnostic procedures.

Please inquire for CE-mark IVD use.

Pseudovirus validation product
  • Lyophilized reagent
  • Compatible with Monkeypox Virus Real-time PCR Test for validation studies

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Antigen Rapid Test

Antigen Rapid Test

The Monkeypox Antigen Rapid Test Kit (Colloidal Gold) is a colloidal gold immunochromatography assay intended for the qualitative detection of Monkeypox Viral Antigen from individuals infected with the virus. Sample types compatible with the Monkeypox Antigen Rapid Test Kit (Colloidal Gold) includes lesion swab, nasal swab, and nasopharyngeal swab.

For Research Use Only.

Not for use in diagnostic procedures.

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Recombinant Proteins

Recombinant Proteins

Viral proteins are potential targets for disease diagnosis, therapeutics and vaccine development. GenScript provides high quality off-the-shelf recombinant Monkeypox virus proteins to support your MPXV research.

Purity: ≥ 95% as analyzed by SDS-PAGE

Endotoxin level: < 0.2 EU/μg of protein by gel clotting method

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