Overview

Neoantigens are immunogenic peptides generated from tumor-specific mutations, serving as critical biomarkers to differentiate cancer cells from normal cells. Their exclusive expression in tumor cells makes them highly suitable and safe targets for cancer immunotherapy.

GenScript offers a one-stop solution for neoantigen peptide services, from research lab to cGMP compliant manufacturing facility. Our offerings can cover your whole neoantigen peptide research life, from early-stage screening, research grade synthesis, to preclinical studies, as well as clinical trials.

Why Choose GenScript

Track records with 20+ years expertise, over 99% success rate

Track records with 20+ years expertise, over 99% success rate

Streamlined supply chain from ISO9001 to cGMP compliance

Streamlined supply chain from ISO9001 to cGMP compliance

cGMP compliance neoantigen peptide with guaranteed sterility

cGMP compliance neoantigen peptide with guaranteed sterility

Research Grade Neoantigen

  • Enhanced Success in Peptide Synthesis with NeoPre 2.0

    Leverages a predictive algorithm to significantly improve the success rate of peptide synthesis, especially for challenging peptides. This innovation ensures the most efficient approach, leading to better and faster outcomes.

  • Tailored Services for PCV Development

    Primary screening services cater to the specific needs of PCV development, offering flexible solutions that guarantee reliable peptides suitable for any phase of development.

  • Proven Track Records

    Having served over 300 academic and industrial customers. NeoPre has consistently delivered superior results. Clients attest to our high success rates (99%) and quick turnaround, with delivery time as fast as 4 weeks.

GMP Neoantigen

  • Dedicated GMP Production Line

    Our facility includes a Grade A isolator dedicated to achieve sterile filtration and aseptic filling assisting human injection purposes.

  • Proven Track Records

    With a strong track record, we've successfully delivered 60+ batches to 20+ companies . Our adaptable GMP manufacturing capabilities guarantee reliability and quality for each project.

  • Cost-Effective and Quick Delivery

    We aim to provide affordable solutions without compromising on quality, offering rapid delivery that meets the needs of both patients and research organizations.

Testimonial

Geoffrey Lynn, Ph.D.

Geoffrey Lynn, Ph.D.

Avidea Technologies' CEO

Screening hundreds of neoantigens in mice to validate the generalizability of SNP-7/8a was a tremendous undertaking that could not have been possible without the diligent efforts of GenScript's peptide chemists who were able to rapidly synthesize even the most challenging sequences at the high purity required.


 Geoffrey Lynn, Ph.D.
Marvin Gee, Ph.D.

Marvin Gee, Ph.D.

3T Biosciences' co-Founder and Head of Target Discovery.

The 3T technology is multi-faceted due to the ability to uncover specialties in any T-cell- mediated disease. 3T Biosciences has been working with GenScript since 2017 to generate thousands of peptides to understand how T-cell receptors recognize their targets. With that information we can better understand how to identify novel targets in solid tumors and generate safe and effective T-cell receptors.

Marvin Gee, Ph.D.

Advantages of GenScript Neoantigen Peptide Service

Enhanced Success in Peptide Synthesis with NeoPre 2.0

Dedicated GMP Production Line

  • Accelerated Delivery Time: Research-grade peptides can be delivered in 5 days, and other peptides within one week, ensuring timely project progress.
  • High Predictability and Success Rates: 86% accurate predictability rate for synthesis difficulty leads to a 98% success rate for difficult neoantigen peptide synthesis.
  • Sequence Modification Feature: The tool can pre-screen and suggest modifications to sequences, helping customers ensure successful synthesis and improve overall outcomes.
  • Improved Product Quality: The system recommends the best synthesis method for each peptide, ensuring consistently high-quality synthesis results.
  • Higher Customer Satisfaction: Faster and more reliable delivery improves client satisfaction and trust in our services.
  • NeoPre; GenScript’s Proprietary Bioinformatics Tool for Difficult Neoantigen Peptide Synthesis
  • GenScript's Technical Advances for Difficult Neoantigen Peptide Synthesis | GenScript
  • Our facility includes a Grade A isolator dedicated to achieve sterile filtration and aseptic filling assisting human injection purposes.
  • Highly customized services, such as different vial sizes and customized single batch filling volumes.
  • Comprehensive sterility assurance system:
    • Contamination Control Strategy (CCS)
    • Aseptic Process Simulation (APS)
    • Vaporized Hydrogen Peroxide (VHP)
    • Sanitize in Place (SIP)
  • Highly customized aseptic processing service
    • Different vials size
    • Different filling volume
    • One batch of up to 3000 vials
Dedicated GMP Production Line

One-Stop Solution for All Your Neoantigen Needs

GenScript’s neoantigen solution streamlines the development of personalized cancer vaccines, offering fast, reliable results at every stage—from design and screening to GMP production and clinical trials—accelerating your path to clinical application.

Design
  • High throughput design: In silico collaboration platform
  • NeoPre: Leverage bioinformatics algorithm, ensure the most efficient approach for every peptide
  • Offer various peptide library services and library design tools
Synthesis
  • Catalog shared antigens for control
  • Synthesis peptides for personalized cancer vaccine
  • Synthesis peptide libraries for screening
Screening
  • Candidate screening: MS/MS (OBOC Library)
  • ELISPOT
in vitro & in vivo studies
  • Cell viability test
  • Animal test
Clinical
  • Process development and scale-up competence
  • Regulatory support
  • Grade A isolator dedicated to achieve sterile filtration and aseptic filling for human injection projects.

Check Out GenScript’s Neoantigen Peptide Resources

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