Protein Expression System Engineering
- Date and Time: September 4th, 2020, 11:30 am EDT │8:30 am PDT
- Title: Engineering protein disaggregases to counter the protein misfolding that underpins neurodegeneration
- Speaker: Dr. Meredith Jackrel.
Assistant Professor, Department of Chemistry, Washington University in St. Louis
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Key points:
- Engineering of Hsp104, a protein disaggregase from yeast, to counter the misfolding of proteins that aggregate in ALS and Parkinson's disease;
- How different missense mutations, both conservative and non-conservative, can potentiate Hsp104;
- Uncover variants with improved properties and learn about the mechanism of Hsp104 potentiation by screening large libraries of Hsp104 variants that comprehensively cover the sequence space.
Improving Immunotherapy Efficacy and Safety
- Date and Time: September 1st, 2020, 9:45 am EDT │6:45 am PDT
- Title: Accelerate Antibody Drug Discovery with Single B Cell Technology
- Speaker: Dr. Tina Zhang. Senior Scientist, GenScript Probio.
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Optimizing Protein Expression
- Date and Time: September 2nd, 2020, 11:35 am EDT │8:35 am PDT
- Title: Novel Solution for High Throughput Antibody and Protein Purification using Magnetic Beads
- Speaker: Dr. Sean Taylor. Field Application Scientist Manager, GenScript
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