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Catalog Products » Other Products » Catalog Peptides » Beta Amyloid Peptides » β-Amyloid (1-42), rat

β-Amyloid (1-42), rat

Synonyms Abeta 1-42, ratβ-Amyloid Peptide; βAmyloid Peptide; b-Amyloid Peptide; bAmyloid Peptide; beta-Amyloid Peptide; betaAmyloid Peptide
Description Abeta 1-42 induces a strong membrane destabilization in giant unilamellar vesicles composed of palmitoyloleoyl-phosphatidylcholine, sphingomyelin, and cholesterol, lowering the critical tension of vesicle rupture. Additionally, Abeta 1-42 triggers the induction of sequential leakage of low- and high-molecular-weight markers trapped inside the giant unilamellar vesicles, but preserving the vesicle shape. The Abeta 1-42 sequence confers particular molecular properties to the peptide that, in turn, influence supramolecular properties associated with membranes that may result in toxicity,including: 1) the ability of the peptide to strongly associate with the membrane; 2) a reduction of lateral membrane cohesive forces; and 3) a capacity to break the transbilayer gradient and puncture sealed vesicles.
Molecular Formula C199H307N53O59S1
Molecular Weight 4418.1

Purity > 95%
Gmp Flag 0
Storage Store at -20°C.

Cat. No. Product Name Quantity Price
β-Amyloid (1-42), human - 1 mg
β-Amyloid (1-42), human - 0.5 mg
β-Amyloid (1-40), rat - 0.5 mg
β-Amyloid (25-35) - 5 mg
β-Amyloid (25-35) - 1 mg
β-Amyloid (1-40) - 1 mg
β-Amyloid (1-40) - 0.5 mg
β-Amyloid (1-28) - 0.5 mg
Bastianetto S, et al. Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. Eur J Neurosci. Jan 2006;23(1):55-64.

Chen L, et al. alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats. Neuropharmacology. Feb 2006;50(2):254-268.

Folin M, et al. Apolipoprotein-E modulates the cytotoxic effect of beta-amyloid on rat brain endothelium in an isoform-dependent specific manner. Int J Mol Med. May 2006;17(5):821-826.

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Cat. No. RP10013
Size Price
0.5 mg $176.00
1 mg $309.00