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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Calcineurin Substrate

Calcineurin Substrate

Description Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase. Calcineurin Substrate is useful in assays for protein phosphatase-2B (calcineurin) activity.
Cas No 113873-67-9
Sequence
{ASP}{LEU}{ASP}{VAL}{PRO}{ILE}{PRO}{GLY}{ARG}{PHE}{ASP}{ARG}
{ARG}{VAL}{SER}{VAL}{ALA}{ALA}{GLU}
Sequence Shortening DLDVPIPGRFDRRVSVAAE
Molecular Formula C92H150N28O29
Molecular Weight 2112.4

Purity > 95%
Anaspec Cat No Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu
Storage Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 24 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


Bultynck G, et al. Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol. Cell. Biol. Jun 2006; 26(12): 4729-4745.

Torgan CE, Daniels MP. Calcineurin localization in skeletal muscle offers insights into potential new targets. J. Histochem. Cytochem. Jan 2006; 54(1): 119-128.

Buch MH, et al. The sarcolemmal calcium pump inhibits the calcineurin/nuclear factor of activated T-cell pathway via interaction with the calcineurin A catalytic subunit. J. Biol. Chem. Aug 2005; 280(33): 29479-29487.

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Cat. No. RP10139
Size
Price
1 mg $90.00