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Home » Gene Synthesis & Molecular Biology Services » Calcitonin Gene Related Peptide (CGRP) (8-37), human

Calcitonin Gene Related Peptide (CGRP) (8-37), human

Synonyms α-CGRP 8-37CGRP (8-37), human
Description Calcitonin-Gene-Related Peptide (CGRP) (8-37) inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats. The present study was performed to explore the effect of CGRP (8-37) on the electrical stimulation-evoked discharge frequency of wide dynamic range (WDR) neurons in the dorsal horn of the spinal cord in rats. CGRP (8-37) was applied directly on the dorsal surface of the L3 to L5 spinal cord. The results indicate that CGRP receptors play an important role in the transmission of presumed nociceptive information in the dorsal horn of the spinal cord.
Cas No 119911-68-1
Sequence
{VAL}{THR}{HIS}{ARG}{LEU}{ALA}{GLY}{LEU}{LEU}{SER}{ARG}{SER}{GLY}{GLY}{VAL}{VAL}{LYS}{ASN}{ASN}{PHE}{VAL}{PRO}{THR}{ASN}{VAL}{GLY}{SER}{LYS}{ALA}{PHE}-NH2
Sequence Shortening VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2
Molecular Formula C139H230N44O38
C Terminal NH2
Molecular Weight 3125.59

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Gmp Flag 0
Anaspec Cat No Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
Storage Store the peptide at -20°C. Keep container tightly closed. Store with desiccant.
Note Calcitonin-Gene-Related Peptide (CGRP) (8-37) is a selective antagonist for CGRP receptors and an agonist for calcitonin receptors.


Cat. No.
Product Name
Price
RP11095-0.5
Calcitonin Gene Related Peptide (CGRP), rat - 0.5 mg
$128.00
RP11092-0.5
Calcitonin Gene Related Peptide (CGRP) II, rat - 0.5 mg
$119.00
RP11090-0.5
Calcitonin Gene Related Peptide (CGRP) (8-37), rat - 0.5 mg
$90.00
 

Kawase T, et al. Immature osteoblastic MG63 cells possess two calcitonin gene-related peptide receptor subtypes that respond differently to [Cys(Acm)(2,7)] calcitonin gene-related peptide and CGRP(8-37). Am. J. Physiol., Cell Physiol. Oct 2005; 289(4): C811-818.

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Cat. No. RP11089
Size
Price
0.5 mg $90.00