• English
  • Sign In
  • Contact Us
×
Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Colivelin

Colivelin

Synonyms Colivelin
Description Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). Colivelin is constructed as activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, which is a potent HN derivative. Cell death induced by overexpressed familial Alzheimer's disease (FAD)-causative genes and beta-amyloid (1-43) can be completely suppressed by colivelin. Colivelin administered intraperitoneally suppresses memory impairment and may serve as a novel drug candidate to treat Alzheimer's disease.
Sequence
{Ser}{Ala}{Leu}{Leu}{Arg}{Ser}{Ile}{Pro}{Ala}{Pro}{Ala}{Gly}
{Ala}{Ser}{Arg}{Leu}{Leu}{Leu}{Leu}{Thr}{Gly}{Glu}{Ile}{Asp}
{Leu}{Pro}
Sequence Shortening SALLRSIPAPAGASRLLLLTGEIDLP
Molecular Formula C119H206N32O35
Molecular Weight 2645.1

Gmp Flag 0
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note


Chiba, T. et al. J. Neurosci. 2005 Nov 2;25(44):10252-61.

You can visit "Citations Database" for more citations.







For more documents, please visit "Technical Support".

Cat. No. RP20167
Size
Price
1 mg $153.00