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Approximately 500 putative proteases have been identified in human genome. Through controlling complex proteolytic activities, proteases participate in a wide range of physiological processes. Many of them have been utilized as targets for therapeutic intervention, such as Dipeptidyl Peptidase IV (DPP-IV) and HIV-1 protease for diabetes and AIDS, respectively. However, precise roles of many proteases remain unknown in many diseases.
To speed up the drug discovery process that involves protease targets, GenScript has developed a
protease assay panel for compound screening. Moreover, custom assay development service is available to facilitate your drug screening against protease targets of your interest.
Name: MMP1 Source: Human Substrate: Mca-PLGL-Dpa-AR Reference Compound: NNGH Measured Product: Mca-peptides Detection Technique: Fluorimetry
Name: Factor Xa Source: Human Substrate: CH3OCO-D-CHA-Gly-Arg-pNA-AcOH Reference Compound: PPACK Measured Product: pNA Detection Technique: Colorimetry
GenScript has assembled the largest protease panel in the industry which covers over 70 proteases. Our comprehensive protease panel profiling will boost your capability in evaluating structure-activity relationship (SAR) in drug development process.
If you can't find protease of interest in ready catalog assays, please feel free to contact us for support.
Please contact us mentioning "Discovery Biology", our customer service representatives are available 24 hours a day, Monday through Friday to assist you with
Please contact us if you need immediate assistance.
Please contact us (phone: 1-877-436-7274 or email: email@example.com),if you need immediate assistance.