130399

ENST00000243349, ENSP00000243349; ENSG00000123612

SEQUENCE   493 AA;  54871 MW;  5A10F259679204CB CRC64;
MTRALCSALR QALLLLAAAA ELSPGLKCVC LLCDSSNFTC QTEGACWASV MLTNGKEQVI
KSCVSLPELN AQVFCHSSNN VTKTECCFTD FCNNITLHLP TASPNAPKLG PMELAIIITV
PVCLLSIAAM LTVWACQGRQ CSYRKKKRPN VEEPLSECNL VNAGKTLKDL IYDVTASGSG
SGLPLLVQRT IARTIVLQEI VGKGRFGEVW HGRWCGEDVA VKIFSSRDER SWFREAEIYQ
TVMLRHENIL GFIAADNKDN GTWTQLWLVS EYHEQGSLYD YLNRNIVTVA GMIKLALSIA
SGLAHLHMEI VGTQGKPAIA HRDIKSKNIL VKKCETCAIA DLGLAVKHDS ILNTIDIPQN
PKVGTKRYMA PEMLDDTMNV NIFESFKRAD IYSVGLVYWE IARRCSVGGI VEEYQLPYYD
MVPSDPSIEE MRKVVCDQKF RPSIPNQWQS CEALRVMGRI MRECWYANGA ARLTALRIKK
TISQLCVKED CKA

• "cDNA cloning, expression studies and chromosome mapping of human typeI serine/threonine kinase receptor ALK7 (ACVR1C).";,Bondestam J., Huotari M.-A., Moren A., Ustinov J., Kaivo-Oja N.,Kallio J., Horelli-Kuitunen N., Aaltonen J., Fujii M., Moustakas A.,Ten Dijke P., Otonkoski T., Ritvos O.;,Cytogenet. Cell Genet. 95:157-162(2001).,PubMeb:12063393

• "Identification of novel isoforms of activin receptor-like kinase 7(ALK7) generated by alternative splicing and expression of ALK7 andits ligand, Nodal, in human placenta.";,Roberts H.J., Hu S., Qiu Q., Leung P.C.K., Caniggia I., Gruslin A.,Tsang B., Peng C.;,Biol. Reprod. 68:1719-1726(2003)., PubMeb:12606401 DOI:10.1095/biolreprod.102.013045

• "Generation and annotation of the DNA sequences of human chromosomes 2and 4.";,Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,Waterston R.H., Wilson R.K.;,Nature 434:724-731(2005).,PubMeb:15815621 DOI:10.1038/nature03466

• "The status, quality, and expansion of the NIH full-length cDNAproject: the Mammalian Gene Collection (MGC).";,Genome Res. 14:2121-2127(2004).,PubMeb:15489334 DOI:10.1101/gr.2596504

• "Nodal induces apoptosis and inhibits proliferation in humanepithelial ovarian cancer cells via activin receptor-like kinase 7.";,Xu G., Zhong Y., Munir S., Yang B.B., Tsang B.K., Peng C.;,J. Clin. Endocrinol. Metab. 89:5523-5534(2004).,PubMeb:15531507 DOI:10.1210/jc.2004-0893

• "Patterns of somatic mutation in human cancer genomes.";,Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C.,Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S.,O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S.,Bhamra G., Buck G., Choudhury B., Clements J., Cole J., Dicks E.,Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J.,Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K.,Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T.,West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P.,Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E.,DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E.,Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T.,Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.;,Nature 446:153-158(2007).,PubMeb:17344846 DOI:10.1038/nature05610