Protein Annotations for Cytochrome c oxidase polypeptide VIIb2, CX7B2

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Name	Gene Symbol	Rec Full Name	Protein Information	Quick Quote	Price, Turnaround
CX7B2_HUMAN, Homo sapiens (human)	COX7B2	Cytochrome c oxidase polypeptide VIIb2	Functions		Starting from $1600, 4 weeks
CX7B2_HUMAN, Homo sapiens (human)	COX7B2	Cytochrome c oxidase polypeptide VIIb2	Protein Domains		Quote

Protein Names

Recommended name:	Cytochrome c oxidase subunit 7B2, mitochondrial;
Alternative name(s):	Cytochrome c oxidase polypeptide VIIb2

Protein IDs
(Accession numbers)

UniProtKB	Q8TF08
NCBI RefSeq	NP_570972.2, NM_130902.2.

Organism

Latin Name/ (Common Name)	Homo sapiens (Human).
Taxonomic Identifier (NCBI)	9606

Gene Names

COX7B2 [GenPool]

GeneID

170712

Genome
Annotation (Ensembl)

ENST00000302930, ENSP00000305964; ENSG00000170516

ENST00000355591, ENSP00000347799; ENSG00000170516

ENST00000396533, ENSP00000379784; ENSG00000170516

Protein Sequence

SEQUENCE   81 AA;  9077 MW;  3E9769D2EBF42E25 CRC64;
MMFPLARNAL SSLKIQSILQ SMARHSHVKH SPDFHDKYGN AVLASGTAFC VATWVFTATQ
IGIEWNLSPV GRVTPKEWKH Q

General annotation

Function	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Cofactor
Subunit structure
Subcellular location	Mitochondrion inner membrane (By similarity).
Tissue specificity
Induction
Domain
Post-translational modification
Involvement in disease

References

"Cloning of a new human cDNA similar to Homo sapiens coxVIIb mRNA.";,Jin L., Yu L., Zhao S.Y.;,Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
"The status, quality, and expansion of the NIH full-length cDNAproject: the Mammalian Gene Collection (MGC).";,Genome Res. 14:2121-2127(2004).,PubMeb:15489334 DOI:10.1101/gr.2596504
"A rare polymorphism of the COX7B2 gene in a Cantonese family withnasopharyngeal carcinoma.";,Liang H., Chen H., Shen Y., Feng Q., Jin W., Huang W., Zeng Y.;,Sci. China, Ser. C, Life Sci. 47:449-453(2004).,PubMeb:15623157 DOI:10.1360/03yc0037

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Protein Domain Databases

InterPro	IPR008433, Cyt_c_oxidase_suVIIB. IPR023272, Cyt_c_oxidase_suVIIB_dom.
Gene3D	G3DSA:4.10.51.10, Cyt_c_oxidase_suVIIB_dom; 1.
PANTHER	PTHR16716, COX7B; 1.
Pfam	PF05392, COX7B; 1.
PRINTS
SUPFAM	SSF81423, Cyt_c_oxidase_suVIIB_dom; 1.
PROSITE

3D Structure
Database (PDB)

Entry

Method

Resolution (A)

Chain

Positions

PDBsum

Sequence
Annotation

Feature key	Position(s)	Length	Description
Transit peptide	1 - 25	25	Mitochondrion (By similarity).
Polypeptide chain	26 - 81	56	Cytochrome c oxidase subunit 7B2, /FTId=PRO_0000006161.
Topological domain	26 - 33	8	Mitochondrial matrix (By similarity).
Topological domain	61 - 81	21	Mitochondrial intermembrane (By
Transmembrane region	34 - 60	27	Helical; (By similarity).
Natural variance	27	1	H -> Q. /FTId=VAR_026231.

Protein-protein
Interaction
Databases

DIP
IntAct
MINT
STRING	Q8TF08

Binary Interactions

With

Entry

#Exp.

IntAct

Enzyme and Pathway Databases

Pathway Interaction DB
Reactome

Phylogenomic Database

HOVERGEN	HBG051092
InParanoid	Q8TF08
OMA	HSPDFHD
OrthoDB	EOG444KMX

Proteomics
Database (PRIDE)

Q8TF08

Comparative
Toxicogenomics
Database (CTD)

170712

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