• English
  • Sign In
    Please Sign In
    Sign In
    New to GenScript?
    Register
  • Contact Us
×
Contact us now: +1-877-436-7274
Recombinant Protein & rAb Services
24 hour
Home » Recombinant Protein & rAb Services » PROTBANK™ Protein Database
Email to GenScript

Reviewed (UniProtKB/Swiss-Prot)

Note: Proteins listed in ProtBank™ database are NOT off-the-shelf [catalog] proteins. Customized protein production request can be made for any protein in this database by clicking on the corresponding button under "Quick Quote". Please ensure sequence accuracy and/or make any necessary modifications prior to submitting your quote request

  • THAT AND
  • THAT AND

Reviewed (UniProtKB/Swiss-Prot)


Name Gene Symbol Rec Full Name Protein Information Quick Quote  Price,
Turnaround
DPOA2_CAEEL, Caenorhabditis elegans () div-1 Division delayed protein 1 Functions
wild_type
Starting from $1920,
5 weeks
Protein Domains
mutant
Quote

Protein Names | ProteinIDs  | Organism | Gene Names  | GeneID | Genome Annotation(Ensembl) |  Protein Sequence | 
General annotation |  References | Order
Protein Names
Recommended name:
 DNA polymerase alpha subunit B;
Alternative name(s):
 Division delayed protein 1
Protein IDs
(Accession numbers)
UniProtKB
 Q21625
NCBI RefSeq

NP_499268.1, NM_066867.3.
Organism
Latin Name/
(Common Name)
Caenorhabditis elegans.
Taxonomic Identifier (NCBI)
 6239
Gene Names
 div-1 [GenPool]
GeneID

176439
Genome
Annotation (Ensembl)
Protein Sequence
 
SEQUENCE   581 AA;  64103 MW;  1D4C581B9C977CD0 CRC64;
MAYEFDLEDF NDNLEPFGFN CPAKDHFIEK LEGLCKTFRK SGEDIVDDVV SVMSNLGQKS
VDSGILAKLE ENLEAQAQKT VHTPRSVKKP ARGRVPLAEK SGFILSGDPD DIEKPSHHLT
NSAIAKLEGH FLDFSPFPGS PANEKFLKRA DPSHVVTTIR GKKYQDKGLK GSTKSDDTIR
IISKTPSTLY GGDKSSMVIE AKAQRMADIA HRIQKSFEEI VDWGNPSIPS VDVVYTYGQV
IHDETKDNEK FGEHSVALMI NDEDGTMIRM DFSKMTEDIT LFPGQIIAVR GTNETGEELQ
VDKIFQPAAL PVNPVETDTT KEIWFACGPY TATDNCGYEH LCELLDKVVA EKPDILMLAG
PFVDKKNTFL NKPTFNITYD NLLEDLLLKV KETLVGTKTQ VIIQPNASRD LCVPPVFPSA
PFQQNRKLDK IKKELIFVAD PCIFRISGVE VAMTSSEPIQ ALSNTEFHRS ANQENIDRVA
RLSSHLLTQQ CMYPLEPTEV PASMGDLLDV CCIGSTPHIV FAPTKLAPSA KCVNGSVFIN
SSTLAKGPTG NYAKMSINLN AGELMPGETV ADYAQIQILK I
General annotation
Function
 May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).
Cofactor
Subunit structure
 DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A (By similarity).
Subcellular location

Nucleus.
Tissue specificity
Induction
Domain
Post-translational modification

Involvement in disease

References

  • "Genome sequence of the nematode C. elegans: a platform forinvestigating biology.";,Science 282:2012-2018(1998)., PubMeb:9851916 DOI:10.1126/science.282.5396.2012

  • "DNA replication defects delay cell division and disrupt cell polarityin early Caenorhabditis elegans embryos.";,Encalada S.E., Martin P.R., Phillips J.B., Lyczak R., Hamill D.R.,Swan K.A., Bowerman B.;,Dev. Biol. 228:225-238(2000).,PubMeb:11112326 DOI:10.1006/dbio.2000.9965

Order Custom
Gene & Protein
Secured Online Quotation
Email: [email protected]
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262
Protein Domain Databases | 3D Structure Database  | Sequence Annotation | Protein-protein Interaction Databases  | 
Binary Interactions | Enzyme and Pathway Databases |  Phylogenomic Database | Proteomics Database | 
Comparative Toxicogenomics Database | Order
Protein Domain Databases
InterPro

IPR007185, DNA_pol_alpha/epsilon_bsu.

IPR016722, DNA_pol_alpha_bsu.

IPR013627, Pol_alpha_B_N.
Gene3D
PANTHER
Pfam

PF04042, DNA_pol_E_B; 1.

PF08418, Pol_alpha_B_N; 1.
PRINTS
SUPFAM
PROSITE
3D Structure
Database (PDB)
Entry
Method
Resolution (A)
Chain
Positions
PDBsum
Sequence
Annotation
Feature key
Position(s)
Length
Description
Polypeptide chain 1 - 581 581 DNA polymerase alpha subunit B. /FTId=PRO_0000194038.
Protein-protein
Interaction
Databases
DIP
IntAct

Q21625
MINT
STRING

Q21625
Binary Interactions
With
Entry
#Exp.
IntAct
Enzyme and Pathway Databases
Pathway
Interaction DB
Reactome
Phylogenomic Database
HOVERGEN
InParanoid

Q21625
OMA

KGPTGNY
OrthoDB
Proteomics
Database (PRIDE)

Q21625
Comparative
Toxicogenomics
Database (CTD)

176439
Order Your Custom Protein
Secured Online Quotation
Email: [email protected]
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262