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Reviewed (UniProtKB/Swiss-Prot)

Note: Proteins listed in ProtBank™ database are NOT off-the-shelf [catalog] proteins. Customized protein production request can be made for any protein in this database by clicking on the corresponding button under "Quick Quote". Please ensure sequence accuracy and/or make any necessary modifications prior to submitting your quote request

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Reviewed (UniProtKB/Swiss-Prot)


Name Gene Symbol Rec Full Name Protein Information Quick Quote  Price,
Turnaround
ISK8_MOUSE, Mus musculus (house mouse) Spink8 Serine protease inhibitor Kazal-type 8 Functions
wild_type
Starting from $1600,
4 weeks
Protein Domains
mutant
Quote

Protein Names | ProteinIDs  | Organism | Gene Names  | GeneID | Genome Annotation(Ensembl) |  Protein Sequence | 
General annotation |  References | Order
Protein Names
Recommended name:
 Serine protease inhibitor Kazal-type 8;
Alternative name(s):
Protein IDs
(Accession numbers)
UniProtKB
 Q09TK9
NCBI RefSeq

NP_898959.2, NM_183136.2.
Organism
Latin Name/
(Common Name)
Mus musculus (Mouse).
Taxonomic Identifier (NCBI)
 10090
Gene Names
 Spink8 [GenPool]
GeneID

78709
Genome
Annotation (Ensembl)

ENSMUST00000055821, ENSMUSP00000052529; ENSMUSG00000050074
Protein Sequence
 
SEQUENCE   105 AA;  11778 MW;  8A9DA02483C15A8C CRC64;
MKVIFSVAVL VLASSVWTSL AVDFILPMNF HMTGELLQKT KALCIKNIQL CWILSYFKVS
EPICGSNQVT YEGECHLCSG ILYEDRTVIK VHDGPCEHSS DESEH
General annotation
Function
 Probable serine protease inhibitor.
Cofactor
Subunit structure
Subcellular location

Secreted (Potential).
Tissue specificity
 Expressed in epydiymis, in the cauda, corpus and caput.
Induction
Domain
Post-translational modification

Involvement in disease

References

  • "Novel epididymal protease inhibitors with Kazal or WAP familydomain.";,Jalkanen J., Kotimaeki M., Huhtaniemi I., Poutanen M.;,Biochem. Biophys. Res. Commun. 349:245-254(2006).,PubMeb:16930550 DOI:10.1016/j.bbrc.2006.08.023

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Protein Domain Databases | 3D Structure Database  | Sequence Annotation | Protein-protein Interaction Databases  | 
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Comparative Toxicogenomics Database | Order
Protein Domain Databases
InterPro

IPR002350, Prot_inh_Kazal.
Gene3D
PANTHER
Pfam

PF00050, Kazal_1; 1.
PRINTS
SUPFAM
PROSITE

PS51465, KAZAL_2; 1.
3D Structure
Database (PDB)
Entry
Method
Resolution (A)
Chain
Positions
PDBsum
Sequence
Annotation
Feature key
Position(s)
Length
Description
Signal sequence 1 - 21 21 Potential.
Polypeptide chain 22 - 105 84 Serine protease inhibitor Kazal-type 8. /FTId=PRO_0000302140.
Domain 44 - 98 55 Kazal-like.
Site 53 - 54 2 Reactive bond (Potential).
Disulfide bond 44 - 78 35 By similarity.
Disulfide bond 51 - 75 25 By similarity.
Disulfide bond 64 - 96 33 By similarity.
Protein-protein
Interaction
Databases
DIP
IntAct
MINT
STRING
Binary Interactions
With
Entry
#Exp.
IntAct
Enzyme and Pathway Databases
Pathway
Interaction DB
Reactome
Phylogenomic Database
HOVERGEN

HBG069441
InParanoid

Q09TK9
OMA

GECHLCS
OrthoDB

EOG4KKZ4K
Proteomics
Database (PRIDE)
Comparative
Toxicogenomics
Database (CTD)

646424
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Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262